Protein Alignment CG7794 and mec-12

DIOPT Version :9

• Sequence 1: NP_650674.1
• Gene: CG7794 / 42159
• FlyBaseID: FBgn0038565
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_497663.1
• Gene: mec-12 / 175419
• WormBaseID: WBGene00003175
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 451
• Identity: 241/451 - (53%)
• Similarity: 317/451 - (70%)
• Gaps: 9/451 - (1%)

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRLTQSP----MDDSFLTFFEFTSHQPCVQPRLV 66
            |:|.||||||||||.||||||:||||||..:|::....    .||||.|||..|.....| ||.|
 Worm     3 EVISIHIGQAGVQIGNACWELYCLEHGIQPDGQMPSDKSLGGSDDSFSTFFSETGSGRHV-PRAV 66

  Fly    67 MIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRCRN 131
            |:|.|||||||||||:||:||||:.|||||:|:.:|:|||:..:..|::|.:::.|||:||.|..
 Worm    67 MVDLEPTVIDEIRTGTYRSLFHPEQLITGKEDAANNYARGHYTIGKEIIDLTLDRIRRLADNCTG 131

  Fly   132 LRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHFSM 196
            |:|||||.:.|||:|||..:.:||||..|:||| ..:||.:||:|.:|..:|||||::|..|.::
 Worm   132 LQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKK-AKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 195

  Fly   197 DCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTNLV 261
            :.:|.||:|||||:||||...|::..|:||||||:|.|:|||.|||.||.|...|...|.|||||
 Worm   196 EHSDCSFMVDNEAIYDICRRNLDIERPSYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260

  Fly   262 PYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAP 326
            ||||||:||..::|::....:....:|.|::|..||:..||||:|:|.||||||..||:|||:.|
 Worm   261 PYPRIHFPLATFSPVISAEKAYHEQLSVAEITNMCFEPHNQMVKCDPRHGKYMAVCLLFRGDVVP 325

  Fly   327 NEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAWCR 391
            .::|.|:..||..||.:||||.|||||:|::..||..|||||||...||...:||.|.|..||.|
 Worm   326 KDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVPRAVCMLSNTTAIAEAWAR 390

  Fly   392 LVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEVDASAPTSRRDSDPEED 452
            |.:|||.:|.:||||:.|||||:|||.|:||.|::..|..||.||...   |..|:..|.|
 Worm   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVD---SMEDNGEEGD 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	235/433 (54%)
		PTZ00335	6..439	CDD:185562	237/436 (54%)
mec-12	NP_497663.1	PTZ00335	1..448	CDD:185562	240/449 (53%)
		alpha_tubulin	2..435	CDD:276955	235/433 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S25
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D514396at2759
OrthoFinder	1	1.000	-	-		FOG0000082
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.770