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Protein Alignment CG7794 and TUBA3E

DIOPT Version :10

Sequence 1:	NP_650674.1	Gene:	CG7794 / 42159	FlyBaseID:	FBgn0038565	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_997195.2	Gene:	TUBA3E / 112714	HGNCID:	20765	Length:	450	Species:	Homo sapiens

Alignment Length:	450	Identity:	234/450 - (52%)
Similarity:	315/450 - (70%)	Gaps:	10/450 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRL----TQSPMDDSFLTFFEFTSHQPCVQPRLV 66
            |.|.||:|||||||.||||||:||||||..:|::    |....||||.|||..|.....| ||.|
Human     3 ECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHV-PRAV 66

  Fly    67 MIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRCRN 131
            .:|.||||:||:|||:||.||||:.|||||:|:.||:|||:..:..|::|..::.||::||.|..
Human    67 FVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAASNYARGHYTIGKEIVDLVLDRIRKLADLCTG 131

  Fly   132 LRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHFSM 196
            |:|||:|.:.|||:|||..:.:||||..|:.|| :.:||.:||:|.:|..:|||||::|..|.::
Human   132 LQGFLIFHSFGGGTGSGFASLLMERLSVDYSKK-SKLEFAIYPAPQVSTAVVEPYNSILTTHTTL 195

  Fly   197 DCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTNLV 261
            :.:|.:|:|||||:||||...|::..||||||||:|.|:|||.|||.||.|...|...|.|||||
Human   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260

  Fly   262 PYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAP 326
            ||||||:||..|||::....:....:|.|::|..||:.:||||:|:|.||||||..:|||||:.|
Human   261 PYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVP 325

  Fly   327 NEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAWCR 391
            .::|.|:..||..|:.:||||.|||||:|::..||..|||||||...||...:||.|.|..||.|
Human   326 KDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390

  Fly   392 LVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEVDASAPTSRRDSDPEE 451
            ||:|||.:|.:.|||:.|||||:|||.|:||.|::..|..|..||...:.    :::.||
Human   391 LVHKFDLMYAKWAFVHWYVGEGMEEGEFSEAREDLAALEKDCEEVGVDSV----EAEAEE 446

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.