Protein Alignment CG7794 and TUBB4B

DIOPT Version :9

• Sequence 1: NP_650674.1
• Gene: CG7794 / 42159
• FlyBaseID: FBgn0038565
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_006079.1
• Gene: TUBB4B / 10383
• HGNCID: 20771
• Length: 445
• Species: Homo sapiens
• Alignment Length: 452
• Identity: 150/452 - (33%)
• Similarity: 258/452 - (57%)
• Gaps: 18/452 - (3%)

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRL---TQSPMDDSFLTFFEFTSHQPCVQPRLVM 67
            ||:.:..||.|.||....||:...||||...|..   :...::...:.:.|.|..:  ..||.|:
Human     3 EIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGK--YVPRAVL 65

  Fly    68 IDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRCRNL 132
            :|.||..:|.:|:|.:..:|.||..:.|:..:|:|:|:|:....:||:|..::.:|:.|:.|..|
Human    66 VDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCL 130

  Fly   133 RGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHFSMD 197
            :||.:..::|||:|||:||.::.::.|::..:: :..|.|.|||.:|..:||||||.|:.|..::
Human   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRI-MNTFSVVPSPKVSDTVVEPYNATLSVHQLVE 194

  Fly   198 CADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTNLVP 262
            ..|.::.:|||||||||..||.:..|||.:||.:::..:|..|...||.|......::|..|:||
Human   195 NTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 259

  Fly   263 YPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAPN 327
            :||:|:.:..:|||......|:..::..:||.|.|...|.|..|:|.||:|:....::||.::..
Human   260 FPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMK 324

  Fly   328 EINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAWCRL 392
            |::..:.|::...|..||:|.|...|..|..:||   .|..::.|     .|.|:|.|:..:.|:
Human   325 EVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMSAT-----FIGNSTAIQELFKRI 381

  Fly   393 VNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEV-DASAPTSRRDSDPEEDS 453
            ..:|..:::|:||::.|.|||::|..|.||..|:..||.:|.:. ||   |:..:.:.||::
Human   382 SEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA---TAEEEGEFEEEA 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	145/432 (34%)
		PTZ00335	6..439	CDD:185562	146/436 (33%)
TUBB4B	NP_006079.1	PLN00220	1..427	CDD:215107	145/434 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	426..445		5/18 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810