DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7785 and SPRYD7

DIOPT Version :9

Sequence 1:	NP_650673.1	Gene:	CG7785 / 42158	FlyBaseID:	FBgn0038564	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_065189.1	Gene:	SPRYD7 / 57213	HGNCID:	14297	Length:	196	Species:	Homo sapiens

Alignment Length:	256	Identity:	94/256 - (36%)
Similarity:	126/256 - (49%)	Gaps:	66/256 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFCCLRTCLNGGHIRKPTATSRLRE-PDVHLDAAHMGPDVILLSHQLRVTGTGGVLATAPLVQSK 64
            :.||||.|.:||     |....|:| |.|.||..|||.||:::.:..|:.||||.||:|||.|:|
Human     5 VLCCLRCCRDGG-----TGHIPLKEMPAVQLDTQHMGTDVVIVKNGRRICGTGGCLASAPLHQNK 64

  Fly    65 SYFEVKIQHGGSWSVGLATRQTDLSRKSGGGDRESWCLCSDNATRHNDREEFRPVVQSACTTQPA 129
            ||||.|||..|.|.:|:||::.:|::...|.|..|..:.:|.|..||:.|:.|
Human    65 SYFEFKIQSTGIWGIGVATQKVNLNQIPLGRDMHSLVMRNDGALYHNNEEKNR------------ 117

  Fly   130 RTSNGILNNSAAKAAGLIAIEDLQQEDLLMTTGVASSDVDIGDSLIASPQRDFPDEGDIVGVAFD 194
                                                           .|....|.|||:||:.:|
Human   118 -----------------------------------------------LPANSLPQEGDVVGITYD 135

  Fly   195 HVELNFYFNGKNLEVPFRNVRGAALFPVIYVGNGAILDIILDNFSHGPPPGFERILLEQSL 255
            |||||.|.||||:..|...:|| .::||:||.:.||||.....|.|.||||||:||.||.:
Human   136 HVELNVYLNGKNMHCPASGIRG-TVYPVVYVDDSAILDCQFSEFYHTPPPGFEKILFEQQI 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7785	NP_650673.1	SPRYD7	35..256	CDD:293938	79/221 (36%)
SPRYD7	NP_065189.1	SPRYD7	35..196	CDD:293938	79/221 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149836
Domainoid	1	1.000	116	1.000	Domainoid score	I5988
eggNOG	1	0.900	-	-		E1_KOG4030
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10725
Inparanoid	1	1.050	193	1.000	Inparanoid score	I3854
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48841
OrthoDB	1	1.010	-	-		D1278394at2759
OrthoFinder	1	1.000	-	-		FOG0006352
OrthoInspector	1	1.000	-	-		oto90119
orthoMCL	1	0.900	-	-		OOG6_106411
Panther	1	1.100	-	-	LDO	PTHR20951
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3774
SonicParanoid	1	1.000	-	-		X4623
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800