Protein Alignment Rim and RIMS3

DIOPT Version :9

• Sequence 1: NP_001247163.1
• Gene: Rim / 42150
• FlyBaseID: FBgn0053547
• Length: 2798
• Species: Drosophila melanogaster
• Sequence 2: XP_011540781.1
• Gene: RIMS3 / 9783
• HGNCID: 21292
• Length: 312
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 104/252 - (41%)
• Similarity: 143/252 - (56%)
• Gaps: 24/252 - (9%)

  Fly  2549 VHRSE---EVLPGDITRELRTGGGLGVSLGGAGGAAGGSGGAGGGGLSRGSSSEVDAIEQFFGDG 2610
            :|:.|   :.|..:|.|...|  |:.|.:.......|......|...|..|.
Human    73 IHQFEGATKKLRSNIRRSTET--GIAVEMRSRVTRQGSRESTDGSTNSNSSD------------- 122

  Fly  2611 AGGERFSPSLR--NDGALNEFVDGLGPGQLVGRQVLGAPSLGDIQLSLCHQKGCLEVEVIRARGL 2673
              |....|:.|  .:...::|:|||||.|:||||.|..|.:||:.:::..:.|.||||||.||||
Human   123 --GTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGL 185

  Fly  2674 QQKAQSKMLPAPYVKVYLVSGKRCVDKMKTSSARRTLDPLYQQQLVFKQSYTGCILQITVWGDYG 2738
            ..|..||.|||.|:||||:....|:.|.||...::|.||||||.|:|.:...|.:||:.||||||
Human   186 TPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVIVWGDYG 250

  Fly  2739 RIEKKVFMGVAQIMLDDLNLSNIVIGWYKLFGTTSLVSCPTNIGLGSRRSSIASLDS 2795
            |::.|.|||:||||||:|:||..|.||||||.|:|:..  :.:|..:||.|.:||:|
Human   251 RMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVAD--STLGSLTRRLSQSSLES 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rim	NP_001247163.1	PHD_SF	8..126	CDD:304600
		PDZ_signaling	817..919	CDD:238492
		C2A_RIM1alpha	1148..1272	CDD:175997
		C2B_RIM1alpha	2633..2775	CDD:175994	79/141 (56%)
RIMS3	XP_011540781.1	C2	145..290	CDD:301316	79/146 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143513
Domainoid	1	1.000	144	1.000	Domainoid score	I4609
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6337
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D109268at2759
OrthoFinder	1	1.000	-	-		FOG0000817
OrthoInspector	1	1.000	-	-		otm40596
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.900