DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rim and rims3

DIOPT Version :9

Sequence 1:	NP_001247163.1	Gene:	Rim / 42150	FlyBaseID:	FBgn0053547	Length:	2798	Species:	Drosophila melanogaster
Sequence 2:	NP_001072491.1	Gene:	rims3 / 779946	XenbaseID:	XB-GENE-5959540	Length:	308	Species:	Xenopus tropicalis

Alignment Length:	292	Identity:	112/292 - (38%)
Similarity:	162/292 - (55%)	Gaps:	33/292 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  2520 KKSNSTSQLSA---TGRKRRMGFGKK-----GKNSFTVHRSEEVLPGDITRELR------TGGGL 2570
            :|.||.:..:|   |.:|||...|.|     |.:.::....:...|...|::||      |..|:
Frog    27 EKGNSANPDAAGVTTTKKRRSSLGAKMVAIVGLSQWSKSTLQLNQPDGTTKKLRSNIRRSTETGI 91

  Fly  2571 GVSLGGAGGAAGGSGGAGGGGLSRGSSSEVDAIEQFFGDGAGGERFSPSLR--NDGALNEFVDGL 2633
            .|.:.......|......|...|..|.               |....|:.|  .:...:.|:|||
Frog    92 AVEMRNRVTRQGSRESTDGSTNSNSSD---------------GTFIFPTTRLGAESQFSNFLDGL 141

  Fly  2634 GPGQLVGRQVLGAPSLGDIQLSLCHQKGCLEVEVIRARGLQQKAQSKMLPAPYVKVYLVSGKRCV 2698
            ||.|:||||.|..|.:||:.:.:..:.|.||||||:||||..|..||.:||||:||||:....|:
Frog   142 GPAQIVGRQTLATPPMGDVHIGMVDRNGQLEVEVIQARGLTPKPGSKSIPAPYIKVYLIENGVCL 206

  Fly  2699 DKMKTSSARRTLDPLYQQQLVFKQSYTGCILQITVWGDYGRIEKKVFMGVAQIMLDDLNLSNIVI 2763
            .|.||.::::|.||:|||.|:|.:...|.:||:.|||||||::.|.|||:|||:|::|:||:.|.
Frog   207 SKKKTRTSKKTWDPVYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQILLEELDLSSCVT 271

  Fly  2764 GWYKLFGTTSLVSCPTNIGLGSRRSSIASLDS 2795
            ||||||.|:||..  ::|...:||.|.:||:|
Frog   272 GWYKLFPTSSLAD--SSIAPLTRRLSQSSLES 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rim	NP_001247163.1	PHD_SF	8..126	CDD:304600
		PDZ_signaling	817..919	CDD:238492
		C2A_RIM1alpha	1148..1272	CDD:175997
		C2B_RIM1alpha	2633..2775	CDD:175994	76/141 (54%)
rims3	NP_001072491.1	C2	141..284	CDD:387358	77/142 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	148	1.000	Domainoid score	I4418
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D109268at2759
OrthoFinder	1	1.000	-	-		FOG0000817
OrthoInspector	1	1.000	-	-		otm47771
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010