DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rim and rims4

DIOPT Version :9

Sequence 1:	NP_001247163.1	Gene:	Rim / 42150	FlyBaseID:	FBgn0053547	Length:	2798	Species:	Drosophila melanogaster
Sequence 2:	XP_699547.4	Gene:	rims4 / 570923	ZFINID:	ZDB-GENE-110103-1	Length:	269	Species:	Danio rerio

Alignment Length:	176	Identity:	94/176 - (53%)
Similarity:	128/176 - (72%)	Gaps:	2/176 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly  2620 LRNDGALNEFVDGLGPGQLVGRQVLGAPSLGDIQLSLCHQKGCLEVEVIRARGLQQKAQSKMLPA 2684
            |.:|...::|:||:||.|.||||.|...|:||:::||..:.|.||||||:||||..|..||..||
Zfish    87 LASDAQFSDFLDGMGPAQFVGRQTLATTSMGDVEISLMERSGQLEVEVIQARGLIMKPGSKGPPA 151

  Fly  2685 PYVKVYLVSGKRCVDKMKTSSARRTLDPLYQQQLVFKQSYTGCILQITVWGDYGRIEKKVFMGVA 2749
            .|:||||:....|:.|.||.|.|::|||||.|.|||.:|..|.::|:.|||:|||:::|.|||||
Zfish   152 AYIKVYLLENGICIAKKKTKSVRKSLDPLYNQVLVFSESPQGKVVQVIVWGNYGRMDRKCFMGVA 216

  Fly  2750 QIMLDDLNLSNIVIGWYKLFGTTSLVSCPTNIGLGSRRSSIASLDS 2795
            :|:|::|:||::||||||||.|:|:|. ||...| .|.||..||:|
Zfish   217 RILLEELDLSSMVIGWYKLFPTSSMVD-PTMAPL-IRHSSQLSLES 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rim	NP_001247163.1	PHD_SF	8..126	CDD:304600
		PDZ_signaling	817..919	CDD:238492
		C2A_RIM1alpha	1148..1272	CDD:175997
		C2B_RIM1alpha	2633..2775	CDD:175994	79/141 (56%)
rims4	XP_699547.4	C2B_RIM1alpha	100..245	CDD:175994	80/145 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576376
Domainoid	1	1.000	148	1.000	Domainoid score	I4404
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D109268at2759
OrthoFinder	1	1.000	-	-		FOG0000817
OrthoInspector	1	1.000	-	-		otm24270
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.950