DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rim and NANOGNB

DIOPT Version :9

Sequence 1:	NP_001247163.1	Gene:	Rim / 42150	FlyBaseID:	FBgn0053547	Length:	2798	Species:	Drosophila melanogaster
Sequence 2:	NP_001138937.1	Gene:	NANOGNB / 360030	HGNCID:	24958	Length:	188	Species:	Homo sapiens

Alignment Length:	205	Identity:	33/205 - (16%)
Similarity:	80/205 - (39%)	Gaps:	59/205 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 RAR-MQPMNPQ--QAQQGYGMQQQQQPRSGGAYPDDDPRYYQGELDGLMRQHPHLAHPSQVQPQH 289
            ||| :.|:.|.  :|:.|         ||.|.           |::.::......|.|....|:.
Human     3 RARWLTPVIPALWEAEAG---------RSRGQ-----------EIETILANKKQSAMPWDQDPEQ 47

  Fly   290 TPQSHSQQQQSQHQQQHLMPQQHRPSPQQHSQQQQQQQQHSQQFAARQQQHQQQQHQQQ------ 348
            :..::|:.:|:..|:.....:..|...::..::.:::.|..|:...:::..:|:|:.::
Human    48 STGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKS 112

  Fly   349 ----------------VQQSY---------HAQIHQ---QPQQHPHPHSQQQQHHQQMQHQHGQS 385
                            :|:|.         |.||.|   :.::..:....:::|  :.:|...:|
Human   113 LMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKH--KKKHMRWRS 175

  Fly   386 VPQMGGYQKP 395
            :...|..:.|
Human   176 LCCQGWSRTP 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rim	NP_001247163.1	PHD_SF	8..126	CDD:304600
		PDZ_signaling	817..919	CDD:238492
		C2A_RIM1alpha	1148..1272	CDD:175997
		C2B_RIM1alpha	2633..2775	CDD:175994
NANOGNB	NP_001138937.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	28..106		11/77 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143510
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930