DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rim and rims4

DIOPT Version :9

Sequence 1:	NP_001247163.1	Gene:	Rim / 42150	FlyBaseID:	FBgn0053547	Length:	2798	Species:	Drosophila melanogaster
Sequence 2:	XP_002938058.2	Gene:	rims4 / 100492503	XenbaseID:	XB-GENE-22069078	Length:	271	Species:	Xenopus tropicalis

Alignment Length:	278	Identity:	112/278 - (40%)
Similarity:	158/278 - (56%)	Gaps:	21/278 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly  2520 KKSNSTSQLSATGRKRRMGFGKKGKNSFTVHRSEE--VLPGDITRELRTGGGLGVSLGGAGGAAG 2582
            ::|.|...|||:.....:.|  ...|||.....|:  .|.|.|.|...|  ||.|.:...
Frog     4 ERSQSRISLSASFEALAVYF--PCMNSFDEDDGEDGRKLKGAIQRSTET--GLAVEMPSR----- 59

  Fly  2583 GSGGAGGGGLSRGSSSEVDAIEQFFGDGAGGERFSPSLRNDGALNEFVDGLGPGQLVGRQVLGAP 2647
                    .:.:.|...::.....:|...........|.:||...:|:.|:||.|.||||.|...
Frog    60 --------TVRQASHESIEDSMNSYGSEGNLNYSGMCLASDGQFGDFLSGMGPAQFVGRQTLATT 116

  Fly  2648 SLGDIQLSLCHQKGCLEVEVIRARGLQQKAQSKMLPAPYVKVYLVSGKRCVDKMKTSSARRTLDP 2712
            |:||:::.|..:.|.||||:|:||||..||.||..||.|:||||:....|:.|.||..||::|||
Frog   117 SMGDVEIGLLDRNGQLEVEIIQARGLTAKAGSKTPPAAYIKVYLLENGVCIAKKKTKVARKSLDP 181

  Fly  2713 LYQQQLVFKQSYTGCILQITVWGDYGRIEKKVFMGVAQIMLDDLNLSNIVIGWYKLFGTTSLVSC 2777
            ||.|.|:|.:|..|.:||:.|||:|||:|:|.||||::|:|::|:||::||||||||.|:|:|..
Frog   182 LYNQVLLFTESPQGKVLQVMVWGNYGRMERKHFMGVSRILLEELDLSSMVIGWYKLFPTSSMVDP 246

  Fly  2778 PTNIGLGSRRSSIASLDS 2795
            .|  |...|:||..||:|
Frog   247 ST--GPLLRQSSQLSLES 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rim	NP_001247163.1	PHD_SF	8..126	CDD:304600
		PDZ_signaling	817..919	CDD:238492
		C2A_RIM1alpha	1148..1272	CDD:175997
		C2B_RIM1alpha	2633..2775	CDD:175994	78/141 (55%)
rims4	XP_002938058.2	C2B_RIM1alpha	102..246	CDD:175994	79/143 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	148	1.000	Domainoid score	I4418
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D109268at2759
OrthoFinder	1	1.000	-	-		FOG0000817
OrthoInspector	1	1.000	-	-		otm47771
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010