DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg1 and alg1

DIOPT Version :9

Sequence 1:	NP_650662.1	Gene:	Alg1 / 42146	FlyBaseID:	FBgn0038552	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	XP_012825942.1	Gene:	alg1 / 594994	XenbaseID:	XB-GENE-1006362	Length:	485	Species:	Xenopus tropicalis

Alignment Length:	444	Identity:	202/444 - (45%)
Similarity:	283/444 - (63%)	Gaps:	18/444 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PK-KRNACVIVLGDIGRSPRMQYHAQSLLEENYHVDMIGYLETRPLEELTQHPRCRIHELTAVPV 69
            || .:..||:|||||||||||.|||.||....:.|.:.|:.||.|..:|..|.|..|..::...:
Frog    47 PKGNKRICVLVLGDIGRSPRMTYHALSLARHGFFVTLTGFRETEPHRDLLHHERINIQPVSEFRM 111

  Fly    70 TNLTPKL-RLLFKAFWQTLSLLMALISIGRPSFLLVQNPPGIPTLIVCYLYCAVTRTKLAIDWHN 133
            ..:.|:: :...|...|...|...|:.|...|::::|||||:|::.|.:|:|.:.|::|.|||||
Frog   112 LKVGPRMFQYFIKVIVQAFQLFYILLKIDPLSYIILQNPPGLPSIAVTWLFCVLRRSQLIIDWHN 176

  Fly   134 YTYTVLALGMSKGEQSPLIRLVRRLERYFGSKAHTHFCVTRAMQEDLQQNWGIGPVKVLYDRAPA 198
            |.|::::|  :.|.:.|::|:.:..|:.||..:..:||||.||:|||..||.| ....|||:..:
Frog   177 YGYSIMSL--TNGPKHPIVRIAKWYEKVFGRLSDYNFCVTNAMKEDLMVNWNI-KAATLYDKPAS 238

  Fly   199 QFHPIDLTHKHELYLKLAKDYPQFQAKDAEQSDVLEATALTQ-KLASGVVQYRPQRQAVLVSSTS 262
            .|....:..:|:|::||||:||.|:.....:....|.||.|: ||..|.:.:..:..|:|:||||
Frog   239 IFQETPIEMQHKLFMKLAKEYPPFKYPSQSKCSGTEKTAFTELKLEKGTISFNKECPALLISSTS 303

  Fly   263 WTPDEDFGILLKALQAYE----ETAQAEPLVYPSLLCIITGKGPQKEHYVAEIEKLQWQKVSVIT 323
            ||.||||.||||||:.||    ..|:..|||     |:||||||.||||...|.::|::.:.:.|
Frog   304 WTEDEDFSILLKALEEYELFIRNGAKLPPLV-----CVITGKGPLKEHYSKLIREMQFKNIQICT 363

  Fly   324 PWLEIEDYPTVLASADLGVCLHWSTSGLDLPMKVVDMFGSGLPVCAYDFKCLDELVKHGENGFVF 388
            ||||.||||.:|.||:||||||.|:||||||||||||||..|||||.:||||.|||||||||.:|
Frog   364 PWLEAEDYPLLLGSANLGVCLHKSSSGLDLPMKVVDMFGCCLPVCAINFKCLQELVKHGENGLIF 428

  Fly   389 GDHVQLAEQLRIWFENFPKNPSILETRAGFQRKIQEFQELRWRESWRLIAAPVL 442
            .|.::|||||:..|.:|....|.|:.   ||:.::|..:.||.|:|..|..||:
Frog   429 KDSLELAEQLKDMFTDFTSKSSKLKR---FQQNLRESVQTRWDETWDQIVLPVI 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg1	NP_650662.1	GT1_ALG1_like	6..442	CDD:99986	201/442 (45%)
Alg1	NP_650662.1	PLN02275	7..402	CDD:215155	187/401 (47%)
alg1	XP_012825942.1	GT33_ALG1-like	48..479	CDD:340843	200/441 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	167	1.000	Domainoid score	I3814
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H5387
Inparanoid	1	1.050	341	1.000	Inparanoid score	I2304
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330469at33208
OrthoFinder	1	1.000	-	-		FOG0003761
OrthoInspector	1	1.000	-	-		oto104484
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R40
SonicParanoid	1	1.000	-	-		X3692
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090