Protein Alignment Alg1 and PIGA

DIOPT Version :9

• Sequence 1: NP_650662.1
• Gene: Alg1 / 42146
• FlyBaseID: FBgn0038552
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_002632.1
• Gene: PIGA / 5277
• HGNCID: 8957
• Length: 484
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 87/412 - (21%)
• Similarity: 132/412 - (32%)
• Gaps: 144/412 - (34%)

  Fly   106 NPPGIPTLIVCYLYCAVTR-TKLAIDWHNYTYTVLALGMSKGEQSPLIRLVRRLERYFGSKAHTH 169
            |..|:.:.|.....|.:.| .|:.|..|.|       |..||            .||..|....:
Human    45 NMGGVESHIYQLSQCLIERGHKVIIVTHAY-------GNRKG------------IRYLTSGLKVY 90

  Fly   170 FCVTRAMQEDLQQNWGIGPVKVLYDRAPAQ--FHPIDL------------THKHELYLKLAKDYP 220
            :.                |:||:|:::.|.  ||.:.|            .|.|..:..:|.| .
Human    91 YL----------------PLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSSFSAMAHD-A 138

  Fly   221 QFQAKD---------------AEQSDVLEATALTQKLASG----VVQYRPQRQAVL--------- 257
            .|.||.               |:.|.||....||..|...    .|.|..:...||
Human   139 LFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIV 203

  Fly   258 ------VSSTSWTPD-----EDFGILLKALQAYE-----------ETAQAEPLVYPSLLCIITGK 300
                  |..|.:|||     :...|::.:...|.           |..|.    ||.|..||.|:
Human   204 SVIPNAVDPTDFTPDPFRRHDSITIVVVSRLVYRKGIDLLSGIIPELCQK----YPDLNFIIGGE 264

  Fly   301 GPQKEHYVAEI-EKLQWQKVSVITPWLEIEDYPTVLASADLGVCLHWSTSGLD-LPMKVVDMFGS 363
            || |...:.|: |:.|......:...||.:|...||....:.:    :||..: ..|.:|:....
Human   265 GP-KRIILEEVRERYQLHDRVRLLGALEHKDVRNVLVQGHIFL----NTSLTEAFCMAIVEAASC 324

  Fly   364 GLPVCAYDFKCLDELVKHGENGFVFGDHVQLAEQLRIWFENFPKNPSILETRAGFQRKIQEFQE- 427
            ||.|.:.....:.|:               |.|.|.|..|     ||:.....|.::.|.:.:.
Human   325 GLQVVSTRVGGIPEV---------------LPENLIILCE-----PSVKSLCEGLEKAIFQLKSG 369

  Fly   428 -----------LRWRESWRLIA 438
                       ::...:||.:|
Human   370 TLPAPENIHNIVKTFYTWRNVA 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alg1	NP_650662.1	GT1_ALG1_like	6..442	CDD:99986	87/412 (21%)
		PLN02275	7..402	CDD:215155	79/362 (22%)
PIGA	NP_002632.1	GT1_PIG-A_like	34..432	CDD:99970	87/412 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900