DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Alg1 and alg2

DIOPT Version :9

Sequence 1:	NP_650662.1	Gene:	Alg1 / 42146	FlyBaseID:	FBgn0038552	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	XP_017206821.1	Gene:	alg2 / 403068	ZFINID:	ZDB-GENE-060502-2	Length:	455	Species:	Danio rerio

Alignment Length:	500	Identity:	101/500 - (20%)
Similarity:	174/500 - (34%)	Gaps:	169/500 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RNACVIVLGDIGRSPRMQYHAQSLLEENYHVDMIGYLETRPLEELTQHP---------------- 57
            |..|.|.:.          |:....:|...|::.|..:...:..:..||
Zfish    24 RQLCAIFVS----------HSNKQTDEFVSVNVKGSCQDSMVRVVFLHPDLGIGGAERLVVDAAV 78

  Fly    58 -----RCRIHELTAVPVTNLTPKLRLLFKAFWQTLSLLMALISIGRPSFLLVQNPPGIPTLIVCY 117
                 .|.:...||    :..|:     ..|.:|||..:.::.:|          ..:||.:..|
Zfish    79 ALRSRGCSVQIWTA----HYDPQ-----HCFSETLSPDLPVVCVG----------DWLPTSVFGY 124

  Fly   118 LY--CAVTRTKLAIDWHNYTYTVLALGMSKGEQ------------SPLIRLVRRLERYFGSKAHT 168
            .:  ||..|         ..|..:.|.:..||:            .|.:||.|:.::..   .:.
Zfish   125 FHALCAYLR---------MIYLTIYLVLFSGEEFDVVFCDQVSACIPFLRLARQRKKVL---FYC 177

  Fly   169 HFCVTRAMQEDLQQNWGIGPVKVLYDRAPAQFH----PIDLTHKHELYLKLAKDY---PQFQAKD 226
            ||                 |.::|..|..|...    |||..  .||...:|...   .||.||.
Zfish   178 HF-----------------PDQLLTQRRSALKRLYRGPIDWF--EELTTGMADRILVNSQFTAKV 223

  Fly   227 AEQ---------SDV----LEATALTQKLASGVVQYRPQ-RQAVLVSSTSWTPDEDFGILLKALQ 277
            .:|         :||    |.::|...:: .|:....|: |..:.:|...:...::..:.|:||.
Zfish   224 FKQTFPKLSEIHTDVLYPSLNSSAFDDEV-EGLGGLLPEGRSFIYLSINRYERKKNLPLALQALA 287

  Fly   278 AYEETAQAEPLVYPSLLCIITGKGPQK-----EHYVAEIEKLQWQKVSVITPWLEIEDYPTVLAS 337
            ..::......  :..:..::.|...::     |||    |:|:    |::|. |.:||:.|.|.|
Zfish   288 NLKDRLSVGE--WERVHLVMAGGYDERVVENVEHY----EELR----SLVTS-LGLEDHVTFLRS 341

  Fly   338 ----ADLGVCLHWSTSGLDLPMKVVDMFGSGLPVCAYDFKCLD---------ELVKHGENGFV-- 387
                ..|.: ||.||..|..|..  :.||. :|:.:...:|..         |.|.|.|.||:
Zfish   342 FSDKQKLSL-LHNSTCVLYTPSN--EHFGI-VPIESMYLRCPVIAVNSGGPLESVAHEETGFLCE 402

  Fly   388 -----FGDHVQLAEQLRIWFENFPKNPSILET--RAGFQRKIQEF 425
                 |.:.:|          ||..:|.:.:.  :||.:|..|.|
Zfish   403 PTPERFSEAMQ----------NFVSDPKLKQRMGQAGRERVQQRF 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg1	NP_650662.1	GT1_ALG1_like	6..442	CDD:99986	100/499 (20%)
Alg1	NP_650662.1	PLN02275	7..402	CDD:215155	93/473 (20%)
alg2	XP_017206821.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900