DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg1 and Gys2

DIOPT Version :9

Sequence 1:	NP_650662.1	Gene:	Alg1 / 42146	FlyBaseID:	FBgn0038552	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_663547.2	Gene:	Gys2 / 232493	MGIID:	2385254	Length:	704	Species:	Mus musculus

Alignment Length:	360	Identity:	69/360 - (19%)
Similarity:	122/360 - (33%)	Gaps:	124/360 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RMQYHAQSLLEENYHVDMIGYLETRPLEELTQHPRCRIHELTAVPVTNL--------TP------ 74
            |..||...:...:.|               ..|....:.|:||:...::        ||
Mouse   236 RQIYHRYCMERASVH---------------CAHVFTTVSEITAIEAEHMLKRKPDVVTPNGLNVK 285

  Fly    75 ---------KLRLLFKA---------FW--------QTLSLLMA-------------LISIGRPS 100
                     .|..::||         |:        :||.|.:|             |.|:.|.:
Mouse   286 KFSAVHEFQNLHAMYKARIQDFVRGHFYGHLDFDLEKTLFLFIAGRYEFSNKGADIFLESLSRLN 350

  Fly   101 FLLVQNPPGIPTLIVCYLYCAVTRTKLAIDWHNYTYTVLALGMSKGE--QSPLIRLVRRLERYFG 163
            |||..:...: |::|.::..|.|        :|:....|     ||:  :..|...|..|:..||
Mouse   351 FLLRMHKSNV-TVVVFFIMPAKT--------NNFNVETL-----KGQAVRKQLWDTVHCLKEKFG 401

  Fly   164 SKAHTHFCVTRAMQEDLQQNWGIGPVKVLYDRAPAQFHPIDLT-HKHELYLKLAKDYPQFQAKDA 227
            .|.:..  :.|....|:..         :.||.       ||| .|..::....:..|.....:.
Mouse   402 KKLYDG--LLRGEIPDMNS---------ILDRD-------DLTIMKRAIFSTQRQSLPPVTTHNM 448

  Fly   228 --EQSDVLEATALTQKLASGVVQYRPQRQAVL-----VSSTSWTPDEDF-----GILLKALQAYE 280
              :.:|.:.:|  .:::  |:...|..|..|:     :||||.....|:     |..|....:|.
Mouse   449 IDDSTDPILST--IRRI--GLFNNRADRVKVILHPEFLSSTSPLLPMDYEEFVRGCHLGVFPSYY 509

  Fly   281 E-----TAQAEPLVYPSLLCIITGKGPQKEHYVAE 310
            |     .|:...:..||:...::|.|...:.:||:
Mouse   510 EPWGYTPAECTVMGIPSVTTNLSGFGCFVQEHVAD 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg1	NP_650662.1	GT1_ALG1_like	6..442	CDD:99986	69/360 (19%)
Alg1	NP_650662.1	PLN02275	7..402	CDD:215155	69/360 (19%)
Gys2	NP_663547.2	GT1_Glycogen_synthase_GSY2_like	27..615	CDD:99967	69/360 (19%)
		Glycogen_syn	32..657	CDD:283373	69/360 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	620..704
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900