DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg1 and Piga

DIOPT Version :9

Sequence 1:	NP_650662.1	Gene:	Alg1 / 42146	FlyBaseID:	FBgn0038552	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_035211.2	Gene:	Piga / 18700	MGIID:	99461	Length:	485	Species:	Mus musculus

Alignment Length:	313	Identity:	69/313 - (22%)
Similarity:	103/313 - (32%)	Gaps:	113/313 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 PVKVLYDRAPAQ--FHP------------IDLTHKHELYLKLAKDYPQFQAKD------------ 226
            |::|:|:::.|.  ||.            |.:.|.|..:..:|.| ..|.||.
Mouse    93 PLRVMYNQSTATTLFHSLPLLRYIFVRERITIIHSHSSFSAMAHD-ALFHAKTMGLQTVFTDHSL 156

  Fly   227 ---AEQSDVLEATALTQKLASG----VVQYRPQRQAVL---------------VSSTSWTPD--- 266
               |:.|.||....||..|...    .|.|..:...||               |..|.:|||
Mouse   157 FGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTPDPFR 221

  Fly   267 -------------------EDF--GILLKALQAYEETAQAEPLVYPSLLCIITGKGPQKEHYVAE 310
                               .|.  ||:.:..|.|:|           |..:|.|:|| |...:.|
Mouse   222 RHDSVITVVVVSRLVYRKGTDLLSGIIPELCQKYQE-----------LHFLIGGEGP-KRIILEE 274

  Fly   311 I-EKLQWQKVSVITPWLEIEDYPTVLASADLGVCLHWSTSGLD-LPMKVVDMFGSGLPVCAYDFK 373
            : |:.|......:...||.:|...||....:.:    :||..: ..|.:|:....||.|.:....
Mouse   275 VRERYQLHDRVQLLGALEHKDVRNVLVQGHIFL----NTSLTEAFCMAIVEAASCGLQVVSTKVG 335

  Fly   374 CLDELVKHGENGFVFGDHVQLAEQLRIWFENFPKNPSILETRAGFQRKIQEFQ 426
            .:.|:               |.|.|.|..|     ||:.....|.::.|  ||
Mouse   336 GIPEV---------------LPESLIILCE-----PSVKSLCDGLEKAI--FQ 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg1	NP_650662.1	GT1_ALG1_like	6..442	CDD:99986	69/313 (22%)
Alg1	NP_650662.1	PLN02275	7..402	CDD:215155	62/287 (22%)
Piga	NP_035211.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
Piga	NP_035211.2	GT4_PIG-A-like	34..433	CDD:340827	69/313 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900