DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Odj and AZF1

DIOPT Version :9

Sequence 1:	NP_650661.1	Gene:	Odj / 42145	FlyBaseID:	FBgn0038551	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_014756.3	Gene:	AZF1 / 854280	SGDID:	S000005639	Length:	914	Species:	Saccharomyces cerevisiae

Alignment Length:	329	Identity:	78/329 - (23%)
Similarity:	124/329 - (37%)	Gaps:	91/329 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 SPVLSDPLLKREVLDDTVDTEDDKELLDDD--------KDLMDDDKDFLEDEKPILRYPPAKKIR 150
            |..:|.||.|.:|::   .:|...:.:|:.        |...||...::::|.|....|.:|...
Yeast   435 SSAISRPLDKNDVIE---GSEGLNKHIDESGMQPNIIKKRKKDDSTVYVKNEMPRTDPPMSKDNS 496

  Fly   151 IEDQ-----NFPNRQSP----------------RVRVKRLRVPV-------VEKADSPP------ 181
            ...:     ||..::.|                ..:|.:|.:.:       .||.::..
Yeast   497 TSAEGAAMANFSGKEPPIPDISSVSDDATNLIGATKVDQLMLIIQARKKGFTEKVNTTQDGDLLF 561

  Fly   182 -------PPPRE---HVRKPRKRRPKPKVDRSIKRYVCDQCGWSFNDHSNMKDHKLRHFEEKFSC 236
                   ||..|   .|.||:..:.    .|::|::.|..|            |:|
Yeast   562 NQTMDILPPKSELVGGVEKPKGTQN----TRAVKKHECPYC------------HRL--------- 601

  Fly   237 DECGRKFYTMPLLRLHIRVHHKGEKPYVCKFCGMGFANSPSRCRHERQMHANELVHPCKICGKRF 301
                  |.....|.:|:| .|.|.||:||.:||..|....:...||| :|..|..:.|.||.|:|
Yeast   602 ------FSQATHLEVHVR-SHIGYKPFVCDYCGKRFTQGGNLRTHER-LHTGEKPYSCDICDKKF 658

  Fly   302 NSEKGRL-KHEEGHKSDQPDVHICLTCNKEFKEAQFLHRHYSTKYHRKRVNLLVNGPKEEFQSEV 365
             |.||.| .|...|:..:|.|.....|||.|.:...:..| ..::|::.:|.|.....|...||.
Yeast   659 -SRKGNLAAHLVTHQKLKPFVCKLENCNKTFTQLGNMKAH-QNRFHKETLNALTAKLAEMNPSEN 721

  Fly   366 DPAE 369
            .|.|
Yeast   722 IPLE 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Odj	NP_650661.1	zf-AD	5..77	CDD:214871
		COG5048	<202..343	CDD:227381	42/141 (30%)
		C2H2 Zn finger	209..229	CDD:275368	4/19 (21%)
		C2H2 Zn finger	236..256	CDD:275368	4/19 (21%)
		zf-H2C2_2	249..274	CDD:290200	12/24 (50%)
		C2H2 Zn finger	265..283	CDD:275368	5/17 (29%)
		C2H2 Zn finger	298..314	CDD:275368	7/16 (44%)
		zf-C2H2_jaz	322..347	CDD:288983	5/24 (21%)
		C2H2 Zn finger	324..343	CDD:275368	5/18 (28%)
AZF1	NP_014756.3	COG5048	342..768	CDD:227381	78/329 (24%)
		C2H2 Zn finger	595..615	CDD:275368	8/47 (17%)
		C2H2 Zn finger	623..643	CDD:275368	7/20 (35%)
		C2H2 Zn finger	651..671	CDD:275368	10/20 (50%)
		C2H2 Zn finger	679..702	CDD:275368	5/23 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100