DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Odj and GFI1B

DIOPT Version :9

Sequence 1:NP_650661.1 Gene:Odj / 42145 FlyBaseID:FBgn0038551 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_001358837.1 Gene:GFI1B / 8328 HGNCID:4238 Length:352 Species:Homo sapiens


Alignment Length:369 Identity:91/369 - (24%)
Similarity:129/369 - (34%) Gaps:82/369 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 TPHPKNIFEKRNHRIRMAIEQITGLEIVLENMLPQHICACCLLDLTQAVAFRQRCLETHANLHQR 78
            ||.|:              :|......||..:.|..    | ||.|...  |:..||...||.:.
Human    32 TPVPR--------------DQAPSNSPVLSTLFPNQ----C-LDWTNLK--REPELEQDQNLARM 75

  Fly    79 ISSKAG--VASKGSPEVSPVLSD--PLLKREVLDDTVDTEDDKELLDDDKDLMDDDKDFLEDEKP 139
            ..:..|  |.|:.....|| |||  |..|.....||:.|............:   ...|||....
Human    76 APAPEGPIVLSRPQDGDSP-LSDSPPFYKPSFSWDTLATTYGHSYRQAPSTM---QSAFLEHSVS 136

  Fly   140 ILRYP--PAKKIRIEDQNFPNRQSPRVR----VKRLRVPVVEKADSPPPPPREHVRKPRK-RRPK 197
            :...|  |:.:..::   |..|.||.:.    ||      ..|..|.|.....|||:... .|| 
Human   137 LYGSPLVPSTEPALD---FSLRYSPGMDAYHCVK------CNKVFSTPHGLEVHVRRSHSGTRP- 191

  Fly   198 PKVDRSIKRYVCDQCGWSFNDHSNMKDHKLRHF-----------------------EEKFSCDEC 239
                     :.||.||.:|....:::.|...|.                       |..|.|..|
Human   192 ---------FACDICGKTFGHAVSLEQHTHVHSQGIPAGSSPEPAPDPPGPHFLRQERSFECRMC 247

  Fly   240 GRKFYTMPLLRLHIRVHHKGEKPYVCKFCGMGFANSPSRCRHERQMHANELVHPCKICGKRFNSE 304
            |:.|.....|..|:.: |...:||.|:|||..|.......:| ..:|..|..|.|::|||.|:..
Human   248 GKAFKRSSTLSTHLLI-HSDTRPYPCQFCGKRFHQKSDMKKH-TYIHTGEKPHKCQVCGKAFSQS 310

  Fly   305 KGRLKHEEGHKSDQPDVHICLTCNKEFKEAQFLHRHYSTKYHRK 348
            ...:.|...|...:|  ..|..|.|.|:....|.||..::::.|
Human   311 SNLITHSRKHTGFKP--FSCELCTKGFQRKVDLRRHRESQHNLK 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
OdjNP_650661.1 zf-AD 5..77 CDD:214871 16/62 (26%)
COG5048 <202..343 CDD:227381 42/163 (26%)
C2H2 Zn finger 209..229 CDD:275368 6/19 (32%)
C2H2 Zn finger 236..256 CDD:275368 6/19 (32%)
zf-H2C2_2 249..274 CDD:290200 10/24 (42%)
C2H2 Zn finger 265..283 CDD:275368 6/17 (35%)
C2H2 Zn finger 298..314 CDD:275368 4/15 (27%)
zf-C2H2_jaz 322..347 CDD:288983 7/24 (29%)
C2H2 Zn finger 324..343 CDD:275368 7/18 (39%)
GFI1BNP_001358837.1 C2H2 Zn finger 165..186 CDD:275368 8/26 (31%)
C2H2 Zn finger 194..214 CDD:275368 6/19 (32%)
C2H2 Zn finger 244..264 CDD:275368 6/20 (30%)
COG5048 252..>329 CDD:227381 22/80 (28%)
C2H2 Zn finger 272..292 CDD:275368 6/20 (30%)
zf-H2C2_2 284..309 CDD:372612 9/25 (36%)
C2H2 Zn finger 300..320 CDD:275368 6/19 (32%)
C2H2 Zn finger 328..345 CDD:275368 6/16 (38%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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