DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Odj and znf740a

DIOPT Version :9

Sequence 1:	NP_650661.1	Gene:	Odj / 42145	FlyBaseID:	FBgn0038551	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_005172837.1	Gene:	znf740a / 571608	ZFINID:	ZDB-GENE-030131-5064	Length:	543	Species:	Danio rerio

Alignment Length:	325	Identity:	76/325 - (23%)
Similarity:	115/325 - (35%)	Gaps:	98/325 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 PLLKREVLDDTVDTEDDKELLDDDKDLMDDDKDFLEDEKPILRYPPAKKIRIEDQNFPNRQSPRV 164
            |||.|:..|.|.     ..|||:.:  |...:|....:|......|:|   :.:|:.|..::
Zfish    78 PLLLRKEADFTA-----PRLLDEKE--MRPSEDMQLKKKTRKSGTPSK---VREQDGPAGKA--- 129

  Fly   165 RVKRLRVPVVEKADSPPPPPREHVRKPRKRRPKPKVDRSIKRYVCDQCGWSFNDHSNMKDHKLRH 229
                    ||::..:.|                  :.:..|.::||.|..:|....::|.|.|.|
Zfish   130 --------VVDENGNCP------------------LSKVQKNFICDHCYGAFRSGYHLKRHILIH 168

  Fly   230 FEEK-FSCDECGRKFYTMPLLRLHIRVH---HKGEKPYVCKFCGMGFAN--------------SP 276
            ..|| |:|..|..:|    :.|.|:..|   |.|.|||.|..|.|.|..              .|
Zfish   169 TGEKPFACAVCDMRF----IQRYHLERHSLTHTGVKPYACSMCDMRFFQRYHLERHSLTHTGVKP 229

  Fly   277 SRC---------RHERQMHANELVH------PCKICGKRFNSEKGRLKHEEGHKSDQPDVHICLT 326
            ..|         |:..|.|:  |:|      .|.:|.:||.......:|...|...:|  :.|..
Zfish   230 YACTMCDMRFFQRYHLQRHS--LIHTGVKPYACSMCDRRFFQRYHLQRHSLTHTGVKP--YACSI 290

  Fly   327 CNKEFKEAQFLHRHYST------------------KYHRKRVNLLVNGPKEEFQSEVDPAEFPGY 373
            |:..|.:...|.||..|                  :||.:|.::...|.|....|..|...|..|
Zfish   291 CDMRFFQRYHLQRHSLTHTGVKPFACTMCDMRFFQRYHLQRHSITHTGVKPYACSMCDMRFFHRY 355

Fly 374 373
Zfish 356 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Odj	NP_650661.1	zf-AD	5..77	CDD:214871
		COG5048	<202..343	CDD:227381	47/173 (27%)
		C2H2 Zn finger	209..229	CDD:275368	7/19 (37%)
		C2H2 Zn finger	236..256	CDD:275368	5/19 (26%)
		zf-H2C2_2	249..274	CDD:290200	12/27 (44%)
		C2H2 Zn finger	265..283	CDD:275368	7/40 (18%)
		C2H2 Zn finger	298..314	CDD:275368	3/15 (20%)
		zf-C2H2_jaz	322..347	CDD:288983	8/42 (19%)
		C2H2 Zn finger	324..343	CDD:275368	6/18 (33%)
znf740a	XP_005172837.1	COG5048	138..503	CDD:227381	58/244 (24%)
		C2H2 Zn finger	148..168	CDD:275368	7/19 (37%)
		C2H2 Zn finger	176..196	CDD:275368	6/23 (26%)
		C2H2 Zn finger	204..224	CDD:275368	4/19 (21%)
		C2H2 Zn finger	232..252	CDD:275368	5/21 (24%)
		C2H2 Zn finger	260..280	CDD:275368	5/19 (26%)
		C2H2 Zn finger	288..308	CDD:275368	6/19 (32%)
		C2H2 Zn finger	316..336	CDD:275368	3/19 (16%)
		C2H2 Zn finger	344..364	CDD:275368	4/12 (33%)
		C2H2 Zn finger	372..392	CDD:275368
		C2H2 Zn finger	400..420	CDD:275368
		C2H2 Zn finger	428..448	CDD:275368
		C2H2 Zn finger	456..476	CDD:275368
		C2H2 Zn finger	484..503	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100