DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Odj and Zfp524

DIOPT Version :9

Sequence 1:	NP_650661.1	Gene:	Odj / 42145	FlyBaseID:	FBgn0038551	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001102375.1	Gene:	Zfp524 / 365179	RGDID:	1565485	Length:	314	Species:	Rattus norvegicus

Alignment Length:	312	Identity:	79/312 - (25%)
Similarity:	104/312 - (33%)	Gaps:	108/312 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 EDEKPILRYPPAKKIRIEDQNFPNRQSPRVRVKRLRVPVVEKADSPPPP--------------PR 185
            |:|||:...||.               ||.|..|             ||              ||
  Rat    16 EEEKPLALLPPV---------------PRGRRGR-------------PPGAATTSNRTLKSSLPR 52

  Fly   186 EHVRKPRKRRPKP---KVDRSIKR---YVCDQC-------GWSFNDHSNMKDHKLRHFEEKFSCD 237
            :..|.||..:..|   .||.|...   .:.||.       |.:.:........:..||     |.
  Rat    53 KRGRPPRSVQETPLTAAVDSSGSSDLLLIDDQGVPYTVPEGSAADGPQGSGSKRAPHF-----CP 112

  Fly   238 ECGRKFYTMPLLRLHIRVHHKGEKPYVCKFCGMGFANSPSRCRHERQMHANELVHPCKICGKRFN 302
            .|.|.|..:..|..| .:.|...||:|||.||..|..| |..|....:||......|.:|.:||.
  Rat   113 VCLRAFPYLSDLERH-SISHSELKPHVCKDCGKTFKRS-SHLRRHCNIHAGLRPFRCVLCPRRFR 175

  Fly   303 SEKGRLKHEEG-HKSDQPDVHICLTCNKEFKEAQFLHRHYSTKYHRKRVNLLV------------ 354
             |.|.|.|... |..::|  :.|.:|...|.||..|.|||..| |.:.|.:.|
  Rat   176 -EAGELAHHHRIHSGERP--YQCPSCRVRFTEANTLRRHYKRK-HPELVGMPVRLCPPNPRPQPL 236

  Fly   355 ----------NGPKEEFQSEVDPAEFP------------------GYMEEGQ 378
                      .|.:||.....:|| :|                  |:.:|||
  Rat   237 WDDDEGVPVQEGVQEESPEGKEPA-WPISSTSPLSGCTAGGSAGAGHGQEGQ 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Odj	NP_650661.1	zf-AD	5..77	CDD:214871
		COG5048	<202..343	CDD:227381	45/151 (30%)
		C2H2 Zn finger	209..229	CDD:275368	3/26 (12%)
		C2H2 Zn finger	236..256	CDD:275368	6/19 (32%)
		zf-H2C2_2	249..274	CDD:290200	11/24 (46%)
		C2H2 Zn finger	265..283	CDD:275368	8/17 (47%)
		C2H2 Zn finger	298..314	CDD:275368	6/16 (38%)
		zf-C2H2_jaz	322..347	CDD:288983	10/24 (42%)
		C2H2 Zn finger	324..343	CDD:275368	9/18 (50%)
Zfp524	NP_001102375.1	COG5048	<102..218	CDD:227381	43/126 (34%)
		C2H2 Zn finger	111..131	CDD:275368	6/20 (30%)
		zf-H2C2_2	123..148	CDD:290200	11/25 (44%)
		C2H2 Zn finger	139..159	CDD:275368	8/20 (40%)
		zf-H2C2_2	151..174	CDD:290200	5/22 (23%)
		C2H2 Zn finger	167..187	CDD:275368	8/20 (40%)
		zf-H2C2_2	179..203	CDD:290200	6/25 (24%)
		C2H2 Zn finger	195..216	CDD:275368	10/21 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100