DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Odj and Zfp810

DIOPT Version :9

Sequence 1:	NP_650661.1	Gene:	Odj / 42145	FlyBaseID:	FBgn0038551	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_011240774.1	Gene:	Zfp810 / 235050	MGIID:	2384563	Length:	466	Species:	Mus musculus

Alignment Length:	335	Identity:	87/335 - (25%)
Similarity:	130/335 - (38%)	Gaps:	82/335 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 LDLTQAVAFRQRCLETHA----------------NLHQRIS--SKAGVASKGSPEVSPVLSDPLL 102
            ||..|...:|...|||::                ||.|.:.  |.||.:......|:.|.|
Mouse    21 LDAAQRTLYRDVMLETYSSLVSLGHCMAKPELIFNLEQGLGPRSTAGASVWNLSGVNKVSS---- 81

  Fly   103 KREVLDDTVDTED--------------DKELLDDDKDLMDDDKDFLEDEKPILRYPPAKKIRIE- 152
                |.||:...|              ::||::..|  :|.:   |:..:.|.|  .||....|
Mouse    82 ----LVDTIQENDSRHFWQIEINSHTANEELVEVGK--IDAE---LKIHEEIHR--GAKSYECEV 135

  Fly   153 -------------DQNFPNRQSPRVRVKRLRVPVVEKADSPPPPPREHVRKPRKRRPKPKVDRSI 204
                         .|::...::| ...|:.|     :|..|.....::.|..|..:|
Mouse   136 CLEAFYLKPQYSTKQSYHTCENP-CDCKKCR-----EAFYPKSTLSQYQRLERGEKP-------- 186

  Fly   205 KRYVCDQCGWSFNDHSNMKDHKLRHFEEK-FSCDECGRKFYTMPLLRLHIRVHHKGEKPYVCKFC 268
              :.|.:||.||...|::..|:..|..|| :.|.||.:.||:...|.:|:|: |.|||||.||.|
Mouse   187 --HACLECGKSFYCKSHLTVHQRTHTGEKPYDCKECRKAFYSKSQLNVHLRI-HTGEKPYECKDC 248

  Fly   269 GMGFANSPSRCRHERQMHANELVHPCKICGKRFNSEKGRLKHEEGHKSDQPDVHICLTCNKEFKE 333
            ...|..:.....|:| .|..|..:.||:|.|.|........|...|..::|  :.|..|||.|..
Mouse   249 RKAFYRNSDLTVHQR-THTGEKPYECKVCRKAFYCNSQLTVHHRTHTGEKP--YECQVCNKAFYC 310

  Fly   334 AQFLHRHYST 343
            ...|..|:.|
Mouse   311 KSQLAVHHRT 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Odj	NP_650661.1	zf-AD	5..77	CDD:214871	9/36 (25%)
		COG5048	<202..343	CDD:227381	47/141 (33%)
		C2H2 Zn finger	209..229	CDD:275368	7/19 (37%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		zf-H2C2_2	249..274	CDD:290200	13/24 (54%)
		C2H2 Zn finger	265..283	CDD:275368	5/17 (29%)
		C2H2 Zn finger	298..314	CDD:275368	3/15 (20%)
		zf-C2H2_jaz	322..347	CDD:288983	8/22 (36%)
		C2H2 Zn finger	324..343	CDD:275368	7/18 (39%)
Zfp810	XP_011240774.1	KRAB	4..59	CDD:214630	9/37 (24%)
		C2H2 Zn finger	133..153	CDD:275368	2/19 (11%)
		C2H2 Zn finger	161..181	CDD:275368	5/24 (21%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		COG5048	<199..373	CDD:227381	43/126 (34%)
		C2H2 Zn finger	217..237	CDD:275368	8/20 (40%)
		C2H2 Zn finger	245..265	CDD:275368	6/20 (30%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		C2H2 Zn finger	301..321	CDD:275368	8/20 (40%)
		C2H2 Zn finger	329..349	CDD:275368
		C2H2 Zn finger	357..377	CDD:275368
		zf-H2C2_2	369..392	CDD:372612
		C2H2 Zn finger	385..405	CDD:275368
		zf-H2C2_2	398..420	CDD:372612
		C2H2 Zn finger	413..433	CDD:275368
		C2H2 Zn finger	441..461	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000