DRSC/TRiP Functional Genomics Resources

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Protein Alignment Odj and E4F1

DIOPT Version :9

Sequence 1:NP_650661.1 Gene:Odj / 42145 FlyBaseID:FBgn0038551 Length:430 Species:Drosophila melanogaster
Sequence 2:XP_005255212.1 Gene:E4F1 / 1877 HGNCID:3121 Length:837 Species:Homo sapiens


Alignment Length:508 Identity:116/508 - (22%)
Similarity:179/508 - (35%) Gaps:131/508 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 ECRICGERIFTP-----HPKNIFEKRNHRIRMAIEQITGLEIVLENMLPQHICACCLLDLTQAVA 63
            ||::||....|.     |.:...::|.::....     |........|.:|:.:  |...|:.:.
Human   274 ECKLCGASFRTKGSLIRHHRRHTDERPYKCSKC-----GKSFRESGALTRHLKS--LTPCTEKIR 331

  Fly    64 FRQRCLETHANLHQRISSKAGVASKGSP---------EVSPVL---------------------- 97
            |........:....|..|.||.|..|:.         |.|||:                      
Human   332 FSVSKDVVVSKEDARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELS 396

  Fly    98 -------SDPLLKREVLDDTVDTEDDKE-LLDDDKDLMDDDKDFLE---DEKPILRYPPAKKIRI 151
                   .:|.:.:|:   ...:|..:| ||   ...|.:....||   .|:..|...||.....
Human   397 LGMKALAPEPPVSQEL---PCSSEGSRENLL---HQAMQNSGIVLERAAGEEGALEPAPAAGSSP 455

  Fly   152 EDQNFPNRQSPRVRVKRLRVPVVEKADSPP---PPPR------------EHVRKPRKRRPKPKVD 201
            :.......|.|.:.|:.|...|..:|.:.|   |.|:            .|.|.....||     
Human   456 QPLAVAAPQLPVLEVQPLETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRP----- 515

  Fly   202 RSIKRYVCDQCGWSFNDHSNMKDHKLRHF-EEKFSCDECGRKFYTMPLLRLHIRVHHKGEKPYVC 265
                 :.|.|||.:|.....:|.|:..|. |.:|.|.:||:.:.|:..:|.|.|| |..|:||.|
Human   516 -----FACAQCGKAFPKAYLLKKHQEVHVRERRFRCGDCGKLYKTIAHVRGHRRV-HSDERPYPC 574

  Fly   266 KFCGMGFANSPSRCRHERQMHANELVHPCKICGKRFNSEKGRL-KHEEGHKSDQPDVHICLTCNK 329
            ..||..:....::..|.| .|..|..|.|:.|.:.|. |||.| :|...|..::|  ..|..|.:
Human   575 PKCGKRYKTKNAQQVHFR-THLEEKPHVCQFCSRGFR-EKGSLVRHVRHHTGEKP--FKCYKCGR 635

  Fly   330 EFKEAQFLHRHYSTK---------------YHRKRVNLLVNGPKE---EFQSEVDPAEFPGYMEE 376
            .|.|...|:||..||               .......:|...|..   ||.|.|  |:...|:.|
Human   636 GFAEHGTLNRHLRTKGGCLLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVV--ADTQEYIIE 698

  Fly   377 GQAE----------MEDNQAELD----VMLDNIDEEQYEDHEVL-----QDED 410
            ..|:          :|..|.|:|    .::..|..:....|:::     .||:
Human   699 ATADDAETSEATEIIEGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEE 751

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
OdjNP_650661.1 zf-AD 5..77 CDD:214871 12/76 (16%)
COG5048 <202..343 CDD:227381 47/142 (33%)
C2H2 Zn finger 209..229 CDD:275368 7/19 (37%)
C2H2 Zn finger 236..256 CDD:275368 7/19 (37%)
zf-H2C2_2 249..274 CDD:290200 11/24 (46%)
C2H2 Zn finger 265..283 CDD:275368 4/17 (24%)
C2H2 Zn finger 298..314 CDD:275368 6/16 (38%)
zf-C2H2_jaz 322..347 CDD:288983 9/39 (23%)
C2H2 Zn finger 324..343 CDD:275368 7/18 (39%)
E4F1XP_005255212.1 COG5048 236..648 CDD:227381 96/401 (24%)
C2H2 Zn finger 247..267 CDD:275368
zf-C2H2 273..295 CDD:278523 6/20 (30%)
C2H2 Zn finger 275..295 CDD:275368 5/19 (26%)
zf-H2C2_2 287..310 CDD:290200 3/27 (11%)
zf-C2H2 301..322 CDD:278523 3/25 (12%)
C2H2 Zn finger 303..321 CDD:275368 3/22 (14%)
C2H2 Zn finger 490..510 CDD:275368 3/19 (16%)
DUF45 <506..585 CDD:302795 29/89 (33%)
C2H2 Zn finger 518..538 CDD:275368 7/19 (37%)
C2H2 Zn finger 546..566 CDD:275368 8/20 (40%)
zf-H2C2_2 558..583 CDD:290200 11/25 (44%)
C2H2 Zn finger 574..594 CDD:275368 5/20 (25%)
zf-H2C2_2 588..609 CDD:290200 7/21 (33%)
C2H2 Zn finger 602..622 CDD:275368 8/20 (40%)
zf-H2C2_2 614..638 CDD:290200 6/25 (24%)
C2H2 Zn finger 630..649 CDD:275368 7/18 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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