DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Odj and ZNF524

DIOPT Version :9

Sequence 1:	NP_650661.1	Gene:	Odj / 42145	FlyBaseID:	FBgn0038551	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_011524789.1	Gene:	ZNF524 / 147807	HGNCID:	28322	Length:	370	Species:	Homo sapiens

Alignment Length:	265	Identity:	68/265 - (25%)
Similarity:	95/265 - (35%)	Gaps:	58/265 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 EDEKPILRYPPAKKIRIEDQNFPNRQSPRVRVKRLRVPVVEKADSPPPPPREHVRKPRKRRPKPK 199
            |:|||:...||..:.|...:......|.|.....|              ||:..|.|:..:..|.
Human   122 EEEKPLALSPPVPRGRRGRRPGGATSSNRTLKASL--------------PRKRGRPPKSGQEPPL 172

  Fly   200 V---------------------DRSIKRYVCDQCGWSFNDHSNMKDHKLRHFEEKFSCDECGRKF 243
            |                     |:.:. |...:...:..:.|..:  |..||     |..|.|.|
Human   173 VQVQGVTAPVGSSGGSDLLLIDDQGVP-YTVSEGSAAGPEGSGPR--KAPHF-----CPVCLRAF 229

  Fly   244 YTMPLLRLHIRVHHKGEKPYVCKFCGMGFANSPSRCRHERQMHANELVHPCKICGKRFNSEKGRL 308
            ..:..|..| .:.|...||:.||.||..|..| |..|....:||......|.:|.:||. |.|.|
Human   230 PYLSDLERH-SISHSELKPHQCKVCGKTFKRS-SHLRRHCNIHAGLRPFRCPLCPRRFR-EAGEL 291

  Fly   309 KHEEG-HKSDQPDVHICLTCNKEFKEAQFLHRHYSTKYHRKRVNLLVNGPKEEFQSEVDPAEFPG 372
            .|... |..::|  :.|..|...|.||..|.||...| |.:.:.:.:..|        ||...|.
Human   292 AHHHRVHSGERP--YQCPICRLRFTEANTLRRHAKRK-HPEAMGVPLCAP--------DPGSEPP 345

  Fly   373 YMEEG 377
            :.|||
Human   346 WDEEG 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Odj	NP_650661.1	zf-AD	5..77	CDD:214871
		COG5048	<202..343	CDD:227381	42/141 (30%)
		C2H2 Zn finger	209..229	CDD:275368	2/19 (11%)
		C2H2 Zn finger	236..256	CDD:275368	6/19 (32%)
		zf-H2C2_2	249..274	CDD:290200	10/24 (42%)
		C2H2 Zn finger	265..283	CDD:275368	8/17 (47%)
		C2H2 Zn finger	298..314	CDD:275368	6/16 (38%)
		zf-C2H2_jaz	322..347	CDD:288983	9/24 (38%)
		C2H2 Zn finger	324..343	CDD:275368	8/18 (44%)
ZNF524	XP_011524789.1	COG5048	<219..>283	CDD:227381	23/70 (33%)
		C2H2 Zn finger	222..242	CDD:275368	6/20 (30%)
		zf-H2C2_2	234..259	CDD:290200	10/25 (40%)
		C2H2 Zn finger	250..270	CDD:275368	8/20 (40%)
		zf-H2C2_2	262..285	CDD:290200	5/22 (23%)
		C2H2 Zn finger	278..298	CDD:275368	8/20 (40%)
		zf-H2C2_2	290..314	CDD:290200	6/25 (24%)
		C2H2 Zn finger	306..327	CDD:275368	9/21 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100