DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17801 and CG14711

DIOPT Version :9

Sequence 1:	NP_650660.2	Gene:	CG17801 / 42144	FlyBaseID:	FBgn0038550	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	95/365 - (26%)
Similarity:	156/365 - (42%)	Gaps:	52/365 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 CLEVLAKIKDLTGIWLEQNERQPRHICPSCLNDLNTSIKLKKRIQRVHNEATLRRESGLDEDLES 91
            |.|::.||:::..|.|...:..|..:|.||:..|.::.|.::..|  .:|.|. ..:.:..:::|
  Fly    31 CRELVRKIEEVGSIKLVPLQNIPSMLCYSCVERLTSAHKFRELCQ--ESERTF-ATNVVKAEMKS 92

  Fly    92 TVSDIEPEGDSSDLESEESYDSENYPFDKKAEESDIDL-NLAH---EDRRNEPHNPYDSETPLIF 152
            ..:|..|...:.::  |..|:|.|...|  ..|.||.: |:..   ||...|....|::.|.:..
  Fly    93 EPTDEVPHVVADNI--EYIYESANDFID--GVEDDIGMENIMEEPLEDGVGETSQAYETSTVVDD 153

  Fly   153 KHKNPLIETPSFANENLPNKVDA----------------KSPKKGNFIQIGTDLRLLTTYP-SIK 200
            ..::.|:         :||..|:                :..|:|.    |......:.:| |..
  Fly   154 LDEDDLL---------VPNSTDSDYQPIERCRKAKVRKTRMTKRGR----GRPRGASSGHPRSFS 205

  Fly   201 VVKPLALAPEDVAAENVPPAKRTARKMQSLVCPKCGRVFKTPYNLKTHMVRHTGEKNFPCTFCDK 265
            ..:|    |...:.::.|....|     :::|..||.::.....|..||.||..||.|.|..|.|
  Fly   206 EERP----PVQASFKSSPEVSST-----NIMCEICGNIYSKRAALNIHMRRHMAEKPFKCEICSK 261

  Fly   266 RFVTKYLARLHERVRHMGEQPFECNFCSATFFTSTAKSSHERIRHIRDLRYQCDQCTKRFNTKTC 330
            .|........|.|| |.||:||.|.:|:.:|...::...||| .|..:..:.|..|.|.|:....
  Fly   262 SFAGPSELNRHIRV-HTGEKPFLCKYCNRSFADRSSNIRHER-THTNERPFTCSTCGKAFSYSNV 324

  Fly   331 LNKHKFLHSGLKPFDCVICQINFARKATLRSHFDSVAHQK 370
            |..|...|:|.|||.|.:|...|:||..|..|..::.||:
  Fly   325 LKNHMLTHTGEKPFLCRVCNKTFSRKHQLDQHLGTMTHQQ 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17801	NP_650660.2	zf-AD	9..74	CDD:285071	13/46 (28%)
		zf-C2H2	231..252	CDD:278523	6/20 (30%)
		C2H2 Zn finger	232..252	CDD:275368	6/19 (32%)
		zf-H2C2_2	244..269	CDD:290200	12/24 (50%)
		C2H2 Zn finger	260..281	CDD:275368	7/20 (35%)
		C2H2 Zn finger	289..308	CDD:275368	5/18 (28%)
		C2H2 Zn finger	318..338	CDD:275368	6/19 (32%)
		C2H2 Zn finger	346..362	CDD:275368	6/15 (40%)
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071	14/51 (27%)
		C2H2 Zn finger	228..248	CDD:275368	6/19 (32%)
		zf-H2C2_2	240..264	CDD:290200	11/23 (48%)
		COG5048	249..>362	CDD:227381	40/114 (35%)
		C2H2 Zn finger	256..276	CDD:275368	7/20 (35%)
		zf-H2C2_2	268..292	CDD:290200	10/24 (42%)
		C2H2 Zn finger	284..304	CDD:275368	6/20 (30%)
		zf-H2C2_2	299..321	CDD:290200	8/22 (36%)
		C2H2 Zn finger	312..332	CDD:275368	6/19 (32%)
		zf-H2C2_2	325..349	CDD:290200	10/23 (43%)
		C2H2 Zn finger	340..362	CDD:275368	7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960