Protein Alignment CG17801 and topi

DIOPT Version :10

• Sequence 1: NP_650660.2
• Gene: CG17801 / 42144
• FlyBaseID: FBgn0038550
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_649945.1
• Gene: topi / 41199
• FlyBaseID: FBgn0037751
• Length: 814
• Species: Drosophila melanogaster
• Alignment Length: 483
• Identity: 102/483 - (21%)
• Similarity: 163/483 - (33%)
• Gaps: 135/483 - (27%)

  Fly     5 KKPSQCHLCASCFCHLNPTIIFCLEVLAKIKDLTGIWLEQNERQPRHI----------CPSC--- 56
            |.|::|.:|...|.|.: .::..:|     |....:...|...||..|          |.||
  Fly   225 KGPNECTMCDRKFVHAS-GLVRHME-----KHALDLIPSQTSEQPHTIPAAGLHVVVKCNSCGRI 283

  Fly    57 ------------LNDLNTSIKLKKRIQRV------HNEATLRRESGLDEDLESTVSDIEPEGDSS 103
                        ::|...|...:..:.:|      .||..|..|..:|.|.....|:........
  Fly   284 FYDPQVAFRHGLIHDSEHSTMRQSPMTQVPSNRADFNELLLDGEMLIDNDPAFATSNQNTNPPKK 348

  Fly   104 DLES---------------------EESYDSENYPFDKKAE--ESDIDLNLAHEDRRNEPHNPYD 145
            ::.|                     |....|.::..:::.|  ..||.:|.|.|       ....
  Fly   349 EMFSSLILGSVLQCEFCEYIFADIAELLVHSASHVAERRFECTACDIQMNTAKE-------ASIH 406

  Fly   146 SETPLIFKHK--NPLIETPS-----------FANENLPNKVDAKSPKKGNFIQIGTDLRLLTTYP 197
            .:|..||..:  ..|..|.|           |||.:|..:....|               ...:|
  Fly   407 FQTDCIFMREAIRSLNVTLSRYFVCNVCELKFANTDLLQEHRCTS---------------FHYFP 456

  Fly   198 SIKVVKPLALAPEDVAAENVPPA------------------KRT----ARKMQSLVCPKCGRVFK 240
            .:.......|.|.|....|...|                  |.|    |.:::..:|..||:.:.
  Fly   457 RLNENGKKLLLPCDFCDVNFEFAHDFLAHSEEKHLNKKKREKETRNTGAGRIRQYLCDICGKSYT 521

  Fly   241 TPYNLKTHMVRHTGEKNFPC--TFCDKRFVTKYLARLHERVRHMGEQPFECNFCSATFFTSTAKS 303
            ...:|..|:..|.|.|.|.|  ..||::|..:.....|.|..|.||:|:.|..|...|.|.:...
  Fly   522 QSSHLWQHLRFHQGVKPFVCQEENCDRKFTIRPDLNDHIRKCHTGERPYLCLVCGKRFLTGSVFY 586

  Fly   304 SHERIRHIRDLRYQCDQCTKRFNTKTCLNKHKFLHSGLKPFDCVICQINFARKA-------TLRS 361
            .| |:.|..:.||:|::|.|||.....|..|:.:|:|.||:.|:.|...|.::.       ...|
  Fly   587 QH-RLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPYSCLFCTKTFRQRGDRDKHIRARHS 650

  Fly   362 HFDSVAH--------QKRASAILESEEH 381
            |.|:.:.        |...:|..:::.|
  Fly   651 HLDANSRLMMQMQKFQLETAAAQKAQSH 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17801	NP_650660.2	zf-AD	9..76	CDD:462262	16/97 (16%)
		zf-C2H2	231..252	CDD:395048	5/20 (25%)
		C2H2 Zn finger	232..252	CDD:275368	5/19 (26%)
		zf-H2C2_2	244..269	CDD:463886	10/26 (38%)
		C2H2 Zn finger	260..281	CDD:275368	6/22 (27%)
		C2H2 Zn finger	289..308	CDD:275368	5/18 (28%)
		C2H2 Zn finger	318..338	CDD:275368	7/19 (37%)
		C2H2 Zn finger	346..362	CDD:275368	3/22 (14%)
topi	NP_649945.1	C2H2 Zn finger	230..250	CDD:275370	5/25 (20%)
		C2H2 Zn finger	277..297	CDD:275370	3/19 (16%)
		C2H2 Zn finger	431..453	CDD:275368	5/36 (14%)
		COG5048	<450..647	CDD:227381	52/212 (25%)
		C2H2 Zn finger	469..490	CDD:275368	3/20 (15%)
		C2H2 Zn finger	513..564	CDD:275368	15/50 (30%)
		C2H2 Zn finger	541..561	CDD:275368	5/19 (26%)
		C2H2 Zn finger	572..592	CDD:275368	6/20 (30%)
		C2H2 Zn finger	600..620	CDD:275368	7/19 (37%)
		zf-H2C2_2	612..637	CDD:463886	9/24 (38%)
		C2H2 Zn finger	628..646	CDD:275368	3/17 (18%)