DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17801 and nom

DIOPT Version :9

Sequence 1:	NP_650660.2	Gene:	CG17801 / 42144	FlyBaseID:	FBgn0038550	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	89/366 - (24%)
Similarity:	148/366 - (40%)	Gaps:	74/366 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 EVLAKIKDLTGIWLEQNERQPRHICPSCLNDLNTSIKLKKRIQRVHNEATLRRESGLDEDLESTV 93
            ::|.:|:.:|||.|:|....|..:|..|..||.:::             ..||:..|.:.....:
  Fly    28 DILRRIQLITGILLQQIPNAPDMVCFCCQTDLQSAM-------------IFRRQCILQQKKWVPL 79

  Fly    94 SDIEPEGDSSDLESEESYDSENYPFDKKAEESDIDLNLAHEDRRNEPHNPYDSETPLIFKHKNPL 158
            ...:..|     .|||.....|.|..||.         ..:.||..|..|.:....::..
  Fly    80 LQSDKVG-----ASEEKKVEPNDPSTKKK---------TTKRRRGRPRMPLEIVDIVVTN----- 125

  Fly   159 IETPSFANEN-----------LPNKVDAKSPKKGNFIQIGTDLRLLTTYPSIKVVKPLALAPED- 211
             |:.:.|.|:           :.|:.||..          :|:.|          :.:.|..||
  Fly   126 -ESKASAGESVGGDEFDQPVEISNEPDATD----------SDVNL----------EEIDLPDEDG 169

  Fly   212 VAAENVPPAKRTARKMQSLVCPKCGRVFKTPYNLKTHMVRHTGEKNFPCTFCDKRFVTKYLARLH 276
            :.:::..|      .:|...|..||.:.....:|..|...|.|.:.:||..|.|.|:.....:.|
  Fly   170 LESDHDLP------NVQIHKCDTCGIIKNNKSSLVRHQFEHNGIRPYPCKECPKTFLVASELKAH 228

  Fly   277 ERVRHMGEQPFECNFCSATFFTSTAKSSHERIRHIRDLRYQCDQCTKRFNTKTCLNK-HKFLHSG 340
            ....|..|.||.|.:|...:|:...:..|||: |..:..:.||||.|.| |:||:.| |..:|..
  Fly   229 NLTHHTLEPPFACRYCDRRYFSVVGRKKHERV-HTNERPFVCDQCGKAF-TRTCILKAHMAVHQV 291

  Fly   341 LKPFDCVICQINFARKATLRSHFDSVAHQKRASAILESEEH 381
            ::.:.|.:|..:|:.|..|.:||.|..|::.|.|:..|.|:
  Fly   292 VRKYSCDVCDRSFSLKKHLATHFISNTHKRNAEAVTSSSEY 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17801	NP_650660.2	zf-AD	9..74	CDD:285071	12/44 (27%)
		zf-C2H2	231..252	CDD:278523	5/20 (25%)
		C2H2 Zn finger	232..252	CDD:275368	5/19 (26%)
		zf-H2C2_2	244..269	CDD:290200	9/24 (38%)
		C2H2 Zn finger	260..281	CDD:275368	5/20 (25%)
		C2H2 Zn finger	289..308	CDD:275368	5/18 (28%)
		C2H2 Zn finger	318..338	CDD:275368	11/20 (55%)
		C2H2 Zn finger	346..362	CDD:275368	5/15 (33%)
nom	NP_001262384.1	zf-AD	5..76	CDD:214871	15/60 (25%)
		C2H2 Zn finger	184..204	CDD:275368	5/19 (26%)
		C2H2 Zn finger	212..261	CDD:275368	15/49 (31%)
		zf-H2C2_2	255..278	CDD:290200	10/24 (42%)
		C2H2 Zn finger	269..289	CDD:275368	11/20 (55%)
		zf-H2C2_2	282..305	CDD:290200	5/22 (23%)
		C2H2 Zn finger	297..313	CDD:275368	5/15 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.960