DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17801 and prg

DIOPT Version :9

Sequence 1:	NP_650660.2	Gene:	CG17801 / 42144	FlyBaseID:	FBgn0038550	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001260253.1	Gene:	prg / 34177	FlyBaseID:	FBgn0285971	Length:	558	Species:	Drosophila melanogaster

Alignment Length:	407	Identity:	105/407 - (25%)
Similarity:	155/407 - (38%)	Gaps:	95/407 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SQCHLCASCFCHLN----------PTIIFCLEV-LAKI-KDLTGIWLEQNERQPRHICPSCLNDL 60
            |.|.|     ||.|          .|:.||.:| :|:: |.|..:..::||.....||..||..|
  Fly    15 STCRL-----CHHNTDPNSLNIFDDTVQFCKDVSIAEVSKSLWSVQYDRNECLSELICSRCLEIL 74

  Fly    61 NTSIKLKKRIQRVHNEATLRRESGLDEDLESTVSD-------------------------IEPEG 100
            ..:.:|:|.:|        .||..|.|.|:..:.|                         ::||.
  Fly    75 EEAFELRKGMQ--------EREQSLQEQLKEMIKDHPKHRPGLNGNPGVFVPEEGCIIVEVDPEN 131

  Fly   101 DSSDLESEESYDS----ENYPFDKKAEESDIDLNLAHEDRRNEPHNPYDSETPLIFKHKNPLIET 161
            .:...|.|.:..|    |||..|.:.||.|.|     |:...:..|..|.:.||...... :...
  Fly   132 LAESSEEEFALGSDGEYENYDDDDEEEEEDYD-----EEDEEDGQNGEDVDMPLGMDAAQ-MAAQ 190

  Fly   162 PSFANENLPNKVDAKSPKKGNFIQIGTDLRLLTTYPSIKVVKPLALAPEDVAAE--NVPPAKRTA 224
            .|.||.  .|..:|: ||:.          .|..|..:....|......::||.  |.|
  Fly   191 QSVANN--ANTTEAR-PKRA----------FLCQYCDLGFTLPAECQEHELAAHDPNAP------ 236

  Fly   225 RKMQSLVCPKCGRVFKTPYNLKTHM-VRHTGEKNFPCTFCDKRFVTKYLARLHERVRHMGEQPFE 288
                 ..|..|.....|...|.:|: ..|..::.:.|..|.|.||.:...:.|..| |.|.:||.
  Fly   237 -----YCCNFCNIKLVTRPALISHIKTLHDPDRPYVCAHCRKGFVRRSDLKKHTIV-HTGVRPFT 295

  Fly   289 CNFCSATFFTSTAKSSHERIRHIRDLRYQCDQCTKRFNTKTCLNKHKFLHSGLKPFDCVICQINF 353
            ||.||.:|..:|..:.|.|| |.....:.|.||.:.|.|...:.:|...|..:|.|.|..|..:|
  Fly   296 CNVCSKSFSRNTNLTKHMRI-HSGVKPFVCQQCPRSFQTAVEMMRHTRSHGEVKAFQCGRCPYSF 359

  Fly   354 ARKATLRSHFDSVAHQK 370
            :|:..|      :|||:
  Fly   360 SRRDKL------IAHQQ 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17801	NP_650660.2	zf-AD	9..74	CDD:285071	22/76 (29%)
		zf-C2H2	231..252	CDD:278523	5/21 (24%)
		C2H2 Zn finger	232..252	CDD:275368	5/20 (25%)
		zf-H2C2_2	244..269	CDD:290200	7/25 (28%)
		C2H2 Zn finger	260..281	CDD:275368	7/20 (35%)
		C2H2 Zn finger	289..308	CDD:275368	7/18 (39%)
		C2H2 Zn finger	318..338	CDD:275368	6/19 (32%)
		C2H2 Zn finger	346..362	CDD:275368	5/15 (33%)
prg	NP_001260253.1	zf-AD	16..94	CDD:285071	25/90 (28%)
		COG5048	<212..340	CDD:227381	38/140 (27%)
		C2H2 Zn finger	239..260	CDD:275368	5/20 (25%)
		C2H2 Zn finger	268..288	CDD:275368	7/20 (35%)
		zf-H2C2_2	280..305	CDD:290200	11/25 (44%)
		zf-C2H2	294..316	CDD:278523	10/22 (45%)
		C2H2 Zn finger	296..316	CDD:275368	9/20 (45%)
		zf-H2C2_2	308..331	CDD:290200	7/23 (30%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..372	CDD:275368	8/25 (32%)
		C2H2 Zn finger	416..436	CDD:275368
		C2H2 Zn finger	443..464	CDD:275368
		C2H2 Zn finger	470..490	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439350
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030