DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17801 and znf-782

DIOPT Version :9

Sequence 1:	NP_650660.2	Gene:	CG17801 / 42144	FlyBaseID:	FBgn0038550	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_500033.1	Gene:	znf-782 / 190310	WormBaseID:	WBGene00021931	Length:	662	Species:	Caenorhabditis elegans

Alignment Length:	285	Identity:	78/285 - (27%)
Similarity:	117/285 - (41%)	Gaps:	46/285 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 LDEDLESTVSDIEPEGDSSDLESEESYDSENYPFDKKAEESDIDLNLAHEDRRNEPHNPYDSETP 149
            ||....:|.:...|  |...::..|..:.|.|..:...||.:.|..|  |:..|.     ||.:.
Worm     3 LDYHQPTTTNTTLP--DDIHMKDPEEEEFEEYEDELLEEEEEFDEEL--EELENS-----DSASS 58

  Fly   150 LIFKHKNPLIETPSFANENLPNKVDAKSPKKGNFIQIGTDLRLLTTYPSIKVVKPLALAPEDVAA 214
            |: ...:|...:.|..:......:..:||.:|:    |:.                       .:
Worm    59 LV-SAGSPHGSSSSNGSHGSSPPLQVQSPSQGS----GSS-----------------------GS 95

  Fly   215 ENVPPAKRTARKMQSLVCPKCGRVFKTPYNLKTHMVRHTGEKNFPCTFCDKRFVTKYLARLHERV 279
            ....|.||.       :|..||:.|.....|::|...|||||.:.|.||.|.|..|...::|||.
Worm    96 PTGQPEKRH-------ICTVCGKGFSYFSILESHKRSHTGEKPYNCHFCQKTFAQKATLQVHERT 153

  Fly   280 RHMGEQPFECNFCSATFFTSTAKSSHERIRHIRDLRYQCDQCTKRFNTKTCLNKHKFLHSGLKPF 344
             |.||:|::|.:|..||.....|:.||:..|:....|:|.:|.|..::.:.|..||..| |.|.|
Worm   154 -HTGERPYKCRYCEKTFAQYGTKTVHEKSAHLGIRNYKCPKCDKLLSSPSALYTHKKTH-GDKTF 216

  Fly   345 DCVICQINFARKATLRSHFDSVAHQ 369
            .|..|...||.|..|:.|...|..|
Worm   217 RCDFCPKTFALKNYLKLHVKQVHEQ 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17801	NP_650660.2	zf-AD	9..74	CDD:285071
		zf-C2H2	231..252	CDD:278523	6/20 (30%)
		C2H2 Zn finger	232..252	CDD:275368	6/19 (32%)
		zf-H2C2_2	244..269	CDD:290200	12/24 (50%)
		C2H2 Zn finger	260..281	CDD:275368	9/20 (45%)
		C2H2 Zn finger	289..308	CDD:275368	7/18 (39%)
		C2H2 Zn finger	318..338	CDD:275368	6/19 (32%)
		C2H2 Zn finger	346..362	CDD:275368	6/15 (40%)
znf-782	NP_500033.1	C2H2 Zn finger	106..126	CDD:275368	6/19 (32%)
		zf-H2C2_2	119..143	CDD:290200	12/23 (52%)
		C2H2 Zn finger	134..154	CDD:275368	9/20 (45%)
		zf-H2C2_2	147..171	CDD:290200	11/24 (46%)
		C2H2 Zn finger	162..180	CDD:275368	6/17 (35%)
		COG5048	<187..404	CDD:227381	20/56 (36%)
		C2H2 Zn finger	191..211	CDD:275370	6/19 (32%)
		C2H2 Zn finger	218..239	CDD:275368	7/20 (35%)
		C2H2 Zn finger	248..268	CDD:275368
		zf-H2C2_2	260..285	CDD:290200
		C2H2 Zn finger	276..296	CDD:275368
		zf-H2C2_2	288..313	CDD:290200
		C2H2 Zn finger	304..324	CDD:275368
		C2H2 Zn finger	386..403	CDD:275368
		C2H2 Zn finger	424..441	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000