DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG17802 and ZNF154

DIOPT Version :9

Sequence 1:NP_650659.2 Gene:CG17802 / 42143 FlyBaseID:FBgn0038549 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_001078853.1 Gene:ZNF154 / 7710 HGNCID:12939 Length:437 Species:Homo sapiens


Alignment Length:202 Identity:63/202 - (31%)
Similarity:101/202 - (50%) Gaps:20/202 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   216 NEDGDSDTDADSMSDIEATSRQSALDEDKKPRRKYTKRSSPKNDDTDFLKPAK--KKRKTYISQK 278
            :|.|.|.:.:.|::|      ...|...:||   |..|...|:    |.:.:.  :.|:.:.:.:
Human   164 SECGKSFSKSYSLND------HWRLHTGEKP---YECRECGKS----FRQSSSLIQHRRVHTAVR 215

  Fly   279 VHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCD 343
            .|.||.|||.|::|.|...|...|:|.:|:||.||| |.|::....:..|..|.||:||.|..|.
Human   216 PHECDECGKLFSNKSNLIKHRRVHTGERPYECSECG-KSFSQRSALLQHRGVHTGERPYECSECG 279

  Fly   344 ERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTR 408
            :.|.:.:...:|: :||...:.   ::|:.|.|.:..|....:|..||||||.:.|..|..||::
Human   280 KFFTYHSSLIKHQ-KVHSGSRP---YECSECGKSFSQNSSLIEHHRVHTGERPYKCSECGKSFSQ 340

  Fly   409 NSNLKTH 415
            .|.|..|
Human   341 RSALLQH 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17802NP_650659.2 zf-AD 4..74 CDD:285071
C2H2 Zn finger 282..302 CDD:275368 9/19 (47%)
C2H2 Zn finger 310..331 CDD:275368 7/20 (35%)
C2H2 Zn finger 339..360 CDD:275368 4/20 (20%)
C2H2 Zn finger 371..388 CDD:275370 4/16 (25%)
zf-met 398..421 CDD:289631 7/18 (39%)
C2H2 Zn finger 399..417 CDD:275368 7/17 (41%)
ZNF154NP_001078853.1 KRAB 14..>62 CDD:214630
KRAB 14..53 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 110..129
C2H2 Zn finger 135..155 CDD:275368
COG5048 139..>436 CDD:227381 63/202 (31%)
C2H2 Zn finger 163..183 CDD:275368 5/24 (21%)
C2H2 Zn finger 191..211 CDD:275368 4/23 (17%)
C2H2 Zn finger 219..239 CDD:275368 9/19 (47%)
zf-H2C2_2 231..256 CDD:290200 12/25 (48%)
C2H2 Zn finger 247..267 CDD:275368 7/20 (35%)
C2H2 Zn finger 275..295 CDD:275368 4/20 (20%)
zf-H2C2_2 287..312 CDD:290200 6/28 (21%)
C2H2 Zn finger 303..323 CDD:275368 5/19 (26%)
zf-H2C2_2 315..340 CDD:290200 11/24 (46%)
C2H2 Zn finger 331..351 CDD:275368 7/17 (41%)
C2H2 Zn finger 359..379 CDD:275368
zf-H2C2_2 371..396 CDD:290200
C2H2 Zn finger 387..407 CDD:275368
zf-H2C2_2 400..424 CDD:290200
C2H2 Zn finger 415..435 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

Return to query results.
Submit another query.