DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17802 and ZNF124

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001284497.1	Gene:	ZNF124 / 7678	HGNCID:	12907	Length:	351	Species:	Homo sapiens

Alignment Length:	180	Identity:	57/180 - (31%)
Similarity:	86/180 - (47%)	Gaps:	19/180 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 KYTKRSSPKNDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPEC 313
            |...|||...|          ..:|:..:|.:.|.||||.|......:.|...|:|.||:.|.||
Human   185 KAFSRSSHLRD----------HERTHTGEKPYECKHCGKAFRYSNCLHYHERTHTGEKPYVCMEC 239

  Fly   314 GQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRY 378
            |:.......|..||:. |.||:||.|:.|.:.|.:::...:|| :.|..:|.   :.||.|.|.:
Human   240 GKAFSCLSSLQGHIKA-HAGEEPYPCKQCGKAFRYASSLQKHE-KTHIAQKP---YVCNNCGKGF 299

  Fly   379 ESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNL----KTHYRSRQHQNK 424
            ..:.....||..||||:.:.|:.|..:|:|.|.|    |||...:.::.|
Human   300 RCSSSLRDHERTHTGEKPYECQKCGKAFSRASTLWKHKKTHTGEKPYKCK 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..331	CDD:275368	7/20 (35%)
		C2H2 Zn finger	339..360	CDD:275368	5/20 (25%)
		C2H2 Zn finger	371..388	CDD:275370	4/16 (25%)
		zf-met	398..421	CDD:289631	9/26 (35%)
		C2H2 Zn finger	399..417	CDD:275368	9/21 (43%)
ZNF124	NP_001284497.1	KRAB	12..53	CDD:307490
		C2H2 Zn finger	96..116	CDD:275368
		C2H2 Zn finger	124..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368
		COG5048	<176..338	CDD:227381	53/167 (32%)
		C2H2 Zn finger	180..200	CDD:275368	5/24 (21%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		C2H2 Zn finger	236..256	CDD:275368	7/20 (35%)
		C2H2 Zn finger	264..284	CDD:275368	5/20 (25%)
		C2H2 Zn finger	292..312	CDD:275368	6/19 (32%)
		C2H2 Zn finger	320..340	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960