DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG17802 and ZNF24

DIOPT Version :9

Sequence 1:NP_650659.2 Gene:CG17802 / 42143 FlyBaseID:FBgn0038549 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_001362744.1 Gene:ZNF24 / 7572 HGNCID:13032 Length:368 Species:Homo sapiens


Alignment Length:390 Identity:103/390 - (26%)
Similarity:147/390 - (37%) Gaps:111/390 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    91 DPLSDAHEGLKI-----NDAEVEQEVLYEVSYADNEG-------LEEDHDLYKKEEEESEVN--- 140
            ||  |..||..|     .|.|:.::...:..|.|:.|       |.|...|:.:.|..::..   
Human    31 DP--DGEEGSSIPWNHLPDPEIFRQRFRQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILE 93

  Fly   141 ------------------------ENKE-----FEDIACEIPFSKEDD--------EQEQQQEYE 168
                                    ||.|     .||:..|:     ||        .::::...|
Human    94 LVVLEQFVAILPKELQTWVRDHHPENGEEAVTVLEDLESEL-----DDPGQPVSLRRRKREVLVE 153

  Fly   169 DMVDKKTGHDDGEESQECEESQPDEEESQQNEED-EEESQEDDDELWQNEDGDSDTDADSMSDIE 232
            |||.:       ||:|....|:.|..|:|..... |..|....|:..:.|:|......:..|.:|
Human   154 DMVSQ-------EEAQGLPSSELDAVENQLKWASWELHSLRHCDDDGRTENGALAPKQELPSALE 211

  Fly   233 ATSRQSALDEDKKPRRKYTKRSSPKNDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNL 297
            :......|:.......||.:...||........|::||:        ||||.|||.|:......|
Human   212 SHEVPGTLNMGVPQIFKYGETCFPKGRFERKRNPSRKKQ--------HICDECGKHFSQGSALIL 268

  Fly   298 HVLRHSGVKPFECPECGQKEFNR-YILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHR 361
            |...|||.||:.|.||| |.|:| .||..|.|| |.|||||                        
Human   269 HQRIHSGEKPYGCVECG-KAFSRSSILVQHQRV-HTGEKPY------------------------ 307

  Fly   362 NKKTPKNFKCNYCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSRQHQNKLI 426
                    ||..|.|.:..|.....|:.:||||:.:.|..|..|::::|||..|.| |.:..||:
Human   308 --------KCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQR-RHNAEKLL 363

  Fly   427  426
            Human   364  363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17802NP_650659.2 zf-AD 4..74 CDD:285071
C2H2 Zn finger 282..302 CDD:275368 8/19 (42%)
C2H2 Zn finger 310..331 CDD:275368 12/21 (57%)
C2H2 Zn finger 339..360 CDD:275368 0/20 (0%)
C2H2 Zn finger 371..388 CDD:275370 4/16 (25%)
zf-met 398..421 CDD:289631 9/22 (41%)
C2H2 Zn finger 399..417 CDD:275368 7/17 (41%)
ZNF24NP_001362744.1 SCAN 48..160 CDD:128708 20/123 (16%)
COG5048 <249..329 CDD:227381 40/121 (33%)
Necessary and sufficient for nuclear localization 251..301 27/51 (53%)
C2H2 Zn finger 253..273 CDD:275368 8/19 (42%)
C2H2 Zn finger 281..301 CDD:275368 12/21 (57%)
COG5048 305..>358 CDD:227381 22/85 (26%)
C2H2 Zn finger 309..329 CDD:275368 5/19 (26%)
C2H2 Zn finger 337..357 CDD:275368 8/20 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

Return to query results.
Submit another query.