DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and ZNF574

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001317448.1	Gene:	ZNF574 / 64763	HGNCID:	26166	Length:	986	Species:	Homo sapiens

Alignment Length:	152	Identity:	48/152 - (31%)
Similarity:	72/152 - (47%)	Gaps:	5/152 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 LKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNRYILNIHIR 328
            |:..:.:|..:..::.|.|..|||.|..|.:...|:..|:|.:||.||:| .|.||........|
Human   569 LQLTRHQRFVHRLERRHKCSICGKMFKKKSHVRNHLRTHTGERPFPCPDC-SKPFNSPANLARHR 632

  Fly   329 VKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRYESNYQRAKHEVVHTG 393
            :.|.||:||.|..|.:.|..|:...:|  |:...:..|  ::|..|..|:...|:...|...|||
Human   633 LTHTGERPYRCGDCGKAFTQSSTLRQH--RLVHAQHFP--YRCQECGVRFHRPYRLLMHRYHHTG 693

  Fly   394 ERNFHCEVCKVSFTRNSNLKTH 415
            |..:.|..|..||.....|:.|
Human   694 EYPYKCRECPRSFLLRRLLEVH 715

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..331	CDD:275368	7/20 (35%)
		C2H2 Zn finger	339..360	CDD:275368	6/20 (30%)
		C2H2 Zn finger	371..388	CDD:275370	4/16 (25%)
		zf-met	398..421	CDD:289631	6/18 (33%)
		C2H2 Zn finger	399..417	CDD:275368	6/17 (35%)
ZNF574	NP_001317448.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050