DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17802 and CG1792

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	447	Identity:	121/447 - (27%)
Similarity:	198/447 - (44%)	Gaps:	114/447 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRLCGDLIYTQNPVNIFDE-NSKMVRQIALVTGLWLT--DHSKMPRNMCSCCLLSLKSAIAFRQA 66
            ||.||..|:...|.|:|:| ||.|:.||.::|||:|.  ..:::|..:||.|.|.|::|||||:.
  Fly     6 CRTCGLFIFCSTPSNLFEEPNSVMLHQIEVLTGLFLLGGPGNELPPFICSPCELDLQTAIAFRER 70

  Fly    67 CIKTNNRLTIQRRSVEAKDDGCWADPLSDAHEGLKINDAE--------VEQEVLYEVSYADNEGL 123
            .|:|...|                      .|...:.:||        ||:|:.|
  Fly    71 VIRTQKTL----------------------QESPNLGNAELIESFAVGVEKEIQY---------- 103

  Fly   124 EEDHDLYKKEEEESEVNENKEFEDIACEIPFSKEDDEQEQQQEYEDMVDKKTGHDDGEESQECEE 188
                     .||.:|:                          |..|::         .|....||
  Fly   104 ---------AEEVTEI--------------------------EVIDLL---------PEEHLLEE 124

  Fly   189 SQPDEEESQQNEEDEEESQEDDDELWQNEDGDSDTDADSMSDIEATSRQSALDEDKKPRRKYTKR 253
            ::...|..:|||:.:.:....:.:|.::    :.|.....:.::..      |..:..|.::::.
  Fly   125 TEEPYEICEQNEQPQVKVPAQEKKLRRS----TKTTPTVFTSVKFA------DNSQATRTQWSRL 179

  Fly   254 SSPKNDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEF 318
            :   .|:...||..::||..       ||:.||:.||...||.||:|||:|||.|.|.:|.|:.:
  Fly   180 T---EDEVVALKRERRKRDC-------ICEQCGRHFTCPSNFKLHLLRHTGVKSFACDQCSQQFY 234

  Fly   319 NRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRYESNYQ 383
            ...:|..|..: |.|...:.|::|:..:.:::.|.:||...|.|.|.   |.|..|:|.:..:.:
  Fly   235 TATLLRRHQEL-HAGNALFQCRYCEATYSNASGRIQHERMRHTNVKP---FTCKECNKSFAMSGK 295

  Fly   384 RAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSRQHQNKLIAMSAKS---EIDSK 437
            ...|.:.|||.|.|||:.|:|||.|.|:|.:||||:.|.:...|.:|..   |:|.|
  Fly   296 LRTHMLSHTGVRAFHCDSCQVSFVRRSHLTSHYRSKGHAHTSSAQAALDNPVELDVK 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	31/71 (44%)
		C2H2 Zn finger	282..302	CDD:275368	10/19 (53%)
		C2H2 Zn finger	310..331	CDD:275368	5/20 (25%)
		C2H2 Zn finger	339..360	CDD:275368	5/20 (25%)
		C2H2 Zn finger	371..388	CDD:275370	3/16 (19%)
		zf-met	398..421	CDD:289631	13/22 (59%)
		C2H2 Zn finger	399..417	CDD:275368	9/17 (53%)
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	32/95 (34%)
		C2H2 Zn finger	198..218	CDD:275368	10/19 (53%)
		C2H2 Zn finger	226..243	CDD:275368	4/16 (25%)
		C2H2 Zn finger	254..275	CDD:275368	5/20 (25%)
		zf-C2H2	281..303	CDD:278523	5/21 (24%)
		C2H2 Zn finger	283..303	CDD:275368	4/19 (21%)
		zf-H2C2_2	296..320	CDD:290200	12/23 (52%)
		C2H2 Zn finger	311..329	CDD:275368	9/17 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.860