DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17802 and CG4854

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	96/428 - (22%)
Similarity:	159/428 - (37%)	Gaps:	132/428 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QCRLCGDLIYTQNPVNIFDENSKMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQACI 68
            :||:|  |:..::. ::.........:|...||:.|::....|..:|:.|.|.|::|:..|..|.
  Fly    11 KCRIC--LVQPKDE-SLMPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAALKLRSLCQ 72

  Fly    69 KTNNRLTIQRRSVEAKDDGCWADPLSDAHEGLKINDAEVEQEVLYEVSYADNEGLEEDHDLYKKE 133
            :|...|..|:.                             ||:..|:.:.:.|        .||:
  Fly    73 QTEKDLKEQKL-----------------------------QEINIEIVHDEQE--------TKKK 100

  Fly   134 EEESEVNENKEFEDIACEIPFSKEDDEQEQQQEYEDMVDKKTGHDDGEESQECEESQPDEEESQQ 198
            .|..::::|:            ....:.|.:.||.|..|...
  Fly   101 TESRDLSKNE------------ATGSDSELEYEYLDSYDVTL----------------------- 130

  Fly   199 NEEDEEESQED----DDELWQNEDGDS--DTDADSMSDIEATSRQSALDEDKKPRRKYTKRSSPK 257
                  ||.||    .|||...|...|  :....|:|....|..    |||......:|
  Fly   131 ------ESSEDVACSADELVSIEPAISAPEESVYSLSPKPVTFE----DEDSGQAASFT------ 179

  Fly   258 NDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNRYI 322
                                    |:.|...::::.....|:..||..||.||..|.::......
  Fly   180 ------------------------CNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQ 220

  Fly   323 LNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRY-ESNYQRAK 386
            |..|:.. |.|.:||.|.:||.||...:.|.:|: |:|.|::.   :||.:|.:.: .||..|.
  Fly   221 LARHMNT-HTGNRPYKCDYCDSRFADPSTRIKHQ-RIHTNERP---YKCEFCSRSFGYSNVLRV- 279

  Fly   387 HEVVHTGERNFHCEVCKVSFT----RNSNLKTHYRSRQ 420
            |...|||||.|.|:.|:.||:    :||:.|:|.|:::
  Fly   280 HLKTHTGERPFSCQYCQKSFSQLHHKNSHEKSHKRTKE 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	17/69 (25%)
		C2H2 Zn finger	282..302	CDD:275368	3/19 (16%)
		C2H2 Zn finger	310..331	CDD:275368	4/20 (20%)
		C2H2 Zn finger	339..360	CDD:275368	8/20 (40%)
		C2H2 Zn finger	371..388	CDD:275370	5/17 (29%)
		zf-met	398..421	CDD:289631	9/27 (33%)
		C2H2 Zn finger	399..417	CDD:275368	8/21 (38%)
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	10/47 (21%)
		C2H2 Zn finger	180..200	CDD:275368	3/19 (16%)
		zf-H2C2_2	193..217	CDD:290200	8/23 (35%)
		COG5048	201..>258	CDD:227381	21/58 (36%)
		C2H2 Zn finger	208..228	CDD:275368	4/20 (20%)
		zf-H2C2_2	221..244	CDD:290200	10/23 (43%)
		C2H2 Zn finger	236..256	CDD:275368	8/20 (40%)
		zf-H2C2_2	251..273	CDD:290200	7/25 (28%)
		C2H2 Zn finger	264..284	CDD:275368	6/20 (30%)
		zf-H2C2_2	277..301	CDD:290200	12/24 (50%)
		C2H2 Zn finger	292..312	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960