DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17802 and CG17801

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_650660.2	Gene:	CG17801 / 42144	FlyBaseID:	FBgn0038550	Length:	381	Species:	Drosophila melanogaster

Alignment Length:	447	Identity:	116/447 - (25%)
Similarity:	196/447 - (43%)	Gaps:	92/447 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QCRLCGDLIYTQNPVNIFDENSKMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQACI 68
            ||.||.......||..||  ..:::.:|..:||:||..:.:.||::|..||..|.::|..::...
  Fly     9 QCHLCASCFCHLNPTIIF--CLEVLAKIKDLTGIWLEQNERQPRHICPSCLNDLNTSIKLKKRIQ 71

  Fly    69 KTNNRLTIQRRSVEAKDDGCWADPLSDAHEGLKINDAEVEQEVLYEVSYADNEGLEEDHDLYKKE 133
            :.:|..|::|.|                  ||   |.::|..|         ..:|.:.|....|
  Fly    72 RVHNEATLRRES------------------GL---DEDLESTV---------SDIEPEGDSSDLE 106

  Fly   134 EEESEVNENKEFEDIACEIPFSKEDDEQEQQQEYEDMVDKKTGHDDGEESQECEESQPDEEES-- 196
            .|||..:||         .||.|:.:|.:        :|....|:|    :..|...|.:.|:
  Fly   107 SEESYDSEN---------YPFDKKAEESD--------IDLNLAHED----RRNEPHNPYDSETPL 150

  Fly   197 ---QQNEEDEEESQEDDDELWQNEDGDSDTDADSM---------SDIEATSRQSALDEDKKPRRK 249
               .:|...|..|       :.||:..:..||.|.         :|:...:..        |..|
  Fly   151 IFKHKNPLIETPS-------FANENLPNKVDAKSPKKGNFIQIGTDLRLLTTY--------PSIK 200

  Fly   250 YTK--RSSPKNDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPE 312
            ..|  ..:|::...:.:.|||:..:...|.   :|..||:.|....|...|::||:|.|.|.|..
  Fly   201 VVKPLALAPEDVAAENVPPAKRTARKMQSL---VCPKCGRVFKTPYNLKTHMVRHTGEKNFPCTF 262

  Fly   313 CGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVH-RNKKTPKNFKCNYCDK 376
            |.::...:|:..:|.||:|.||:|:.|.||...|..||.:|.||...| |:.:    ::|:.|.|
  Fly   263 CDKRFVTKYLARLHERVRHMGEQPFECNFCSATFFTSTAKSSHERIRHIRDLR----YQCDQCTK 323

  Fly   377 RYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSRQHQNKLIAMSAKSE 433
            |:.:.....||:.:|:|.:.|.|.:|:::|.|.:.|::|:.|..||.:..|:....|
  Fly   324 RFNTKTCLNKHKFLHSGLKPFDCVICQINFARKATLRSHFDSVAHQKRASAILESEE 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	21/69 (30%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		C2H2 Zn finger	310..331	CDD:275368	6/20 (30%)
		C2H2 Zn finger	339..360	CDD:275368	9/20 (45%)
		C2H2 Zn finger	371..388	CDD:275370	5/16 (31%)
		zf-met	398..421	CDD:289631	7/22 (32%)
		C2H2 Zn finger	399..417	CDD:275368	6/17 (35%)
CG17801	NP_650660.2	zf-AD	9..74	CDD:285071	20/66 (30%)
		zf-C2H2	231..252	CDD:278523	6/20 (30%)
		C2H2 Zn finger	232..252	CDD:275368	6/19 (32%)
		zf-H2C2_2	244..269	CDD:290200	9/24 (38%)
		C2H2 Zn finger	260..281	CDD:275368	6/20 (30%)
		C2H2 Zn finger	289..308	CDD:275368	9/18 (50%)
		C2H2 Zn finger	318..338	CDD:275368	6/19 (32%)
		C2H2 Zn finger	346..362	CDD:275368	5/15 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I8018
eggNOG	1	0.900	-	-		E33208_3C61Y
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.760