DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17802 and CG17806

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	483	Identity:	133/483 - (27%)
Similarity:	214/483 - (44%)	Gaps:	115/483 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTPQCRLCGDLIYTQNPVNIFDENSK-MVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFR 64
            ||..||.||.  ..::..::||:.:: ::..|..:||.||.:...:|..:|..|||.|..|||||
  Fly     1 MTTLCRTCGQ--EAEHAKSLFDKEARDVLSNILKLTGFWLRNQPGVPTRICLSCLLDLNDAIAFR 63

  Fly    65 QACIKTNNRLTIQRRSVEAKDDGCWADPLSDAHEGLKINDAEVEQEVLYEVSYADNEGLEEDHDL 129
            :.||:||:                                           |:.:.:|.:||.|
  Fly    64 ERCIRTNS-------------------------------------------SWFEKQGKQEDSD- 84

  Fly   130 YKKEEEESEVNENKEFEDIACEIPFSKEDDEQE----QQQEYEDMVDKKTGHD------------ 178
                .|.:....|...|.....:|.|....::.    |:.:..|.|..||...
  Fly    85 ----TETAREGGNNRLESRVDVMPISIAQPQRRRILPQRSKKVDGVPLKTVETPIYPLVVPEIPP 145

  Fly   179 -DGEESQECEE-----SQPD-----EEESQQNEE----------DEEESQEDDDELWQNE----- 217
             |..:...||:     |:|.     ..||..:||          :|..:.:...|:.:|.
  Fly   146 ADLVDPLRCEDPIQVKSEPQLSSDYPVESMNHEEPASEMPQVMKEEPRTLQVIGEVQKNRRKPRS 210

  Fly   218 ----DGDSDTDADSMSDIEATSRQSALDEDKKPRRKYTKRSSPKNDDTDFLKPAKKKRKTYISQK 278
                :.....|...:.:|::|:       :|....||..|:          |....||...:..:
  Fly   211 KGCLEECPGKDMAKIENIDSTT-------NKTKEEKYATRN----------KWGAAKRAYALEHR 258

  Fly   279 VHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCD 343
            ::.||.|||.|::|||||:|:.||.|.|.|:|.||.:.||.:::||:|:|:|||||.||.|::|.
  Fly   259 LYFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKYCG 323

  Fly   344 ERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTR 408
            :||.:...|..|| |.|:.....:...|:.|.|.::::.....|.||||||:.||||:|:..|.|
  Fly   324 KRFDNCLKRLNHE-RNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFNR 387

  Fly   409 NSNLKTHYRSRQHQNKLIAMSAKSEIDS 436
            .:.|.|||:|:.|:.|:...|...::|:
  Fly   388 RNALATHYKSKHHRLKVEEQSKMPKMDA 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	26/70 (37%)
		C2H2 Zn finger	282..302	CDD:275368	12/19 (63%)
		C2H2 Zn finger	310..331	CDD:275368	9/20 (45%)
		C2H2 Zn finger	339..360	CDD:275368	8/20 (40%)
		C2H2 Zn finger	371..388	CDD:275370	3/16 (19%)
		zf-met	398..421	CDD:289631	11/22 (50%)
		C2H2 Zn finger	399..417	CDD:275368	8/17 (47%)
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071	27/116 (23%)
		zf-C2H2	260..282	CDD:278523	12/21 (57%)
		C2H2 Zn finger	262..282	CDD:275368	12/19 (63%)
		C2H2 Zn finger	290..311	CDD:275368	9/20 (45%)
		COG5048	<298..>383	CDD:227381	36/85 (42%)
		C2H2 Zn finger	319..339	CDD:275368	8/20 (40%)
		C2H2 Zn finger	350..370	CDD:275368	5/19 (26%)
		ZnF_U1	375..407	CDD:197732	14/31 (45%)
		C2H2 Zn finger	378..396	CDD:275368	8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450091
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	1	0.900	-	-		E33208_3C61Y
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.690