DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17802 and CG6808

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster

Alignment Length:	439	Identity:	103/439 - (23%)
Similarity:	175/439 - (39%)	Gaps:	97/439 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRLC---GDLIYTQNPV-NIFDENS-KMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFR 64
            ||.|   |    ||:.: ::|:.|: |::...|   |..:.....:|..:|:.||:.|:....|.
  Fly    10 CRTCRKKG----TQSTLQSLFESNAHKLLISYA---GTSVKPDDGLPDQICTVCLMQLEEVDRFL 67

  Fly    65 QACIKTNNRL-TIQRRSVEAKDDGCWADPLSDAHEGLKINDAEVEQEVLYEVSYADNEGLEEDHD 128
            .||.:::..| ::.|:::.:          :.|.|.|:..| ::||:............:||:..
  Fly    68 SACKQSDAHLRSLVRQTLSS----------ASAFETLEDKD-QLEQKKRARKQNISGRLIEENPI 121

  Fly   129 LYKKEEEESEVNE-------NKEFEDIACEIPFSKEDDEQEQQQEY--EDMVDKKTGHDDGEESQ 184
            .:|.:|...|..:       ||...|...::..:.|:::...|::|  .||       |...|..
  Fly   122 NFKTQENALETTKDDEILPINKFSSDFVFDLNVNAENEKDIHQEDYTISDM-------DLDREIS 179

  Fly   185 ECEESQPDEEESQQNEEDEEESQEDDDELWQNEDGDSDTDADSMSDIEATSRQSALDEDKKPRRK 249
            :...|:...:||....:..:|:.||...|        :..||.:.|:..     |.:.||
  Fly   180 DQNYSETYSQESSAATDSIQETSEDYHNL--------EPSADYVIDLGV-----ACEPDK----- 226

  Fly   250 YTKRSSPKNDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECG 314
                                          :.|..|...:......|.|...|...|..:|..|
  Fly   227 ------------------------------YRCKICSNTYRCLSQLNAHSQVHRKEKDHQCEVC- 260

  Fly   315 QKEFNRYI-LNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRY 378
            ||.|.... |..|:|. |.|||||.|.:|..||..::...:|| |:|.|::.   :.||.|.|.:
  Fly   261 QKTFRAACNLKTHMRT-HTGEKPYQCCYCSRRFADNSTHRKHE-RLHTNERP---YACNICGKTF 320

  Fly   379 ESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSRQHQNKLIA 427
            ..:..|..|..:|:.|::..|.:||..|.....|..|.:|..|  :|||
  Fly   321 SLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAHEKSLAH--RLIA 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	19/73 (26%)
		C2H2 Zn finger	282..302	CDD:275368	4/19 (21%)
		C2H2 Zn finger	310..331	CDD:275368	8/21 (38%)
		C2H2 Zn finger	339..360	CDD:275368	7/20 (35%)
		C2H2 Zn finger	371..388	CDD:275370	5/16 (31%)
		zf-met	398..421	CDD:289631	7/22 (32%)
		C2H2 Zn finger	399..417	CDD:275368	6/17 (35%)
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871	20/75 (27%)
		C2H2 Zn finger	229..249	CDD:275368	4/19 (21%)
		zf-C2H2	255..277	CDD:278523	8/23 (35%)
		C2H2 Zn finger	257..277	CDD:275368	8/21 (38%)
		zf-H2C2_2	269..293	CDD:290200	12/24 (50%)
		C2H2 Zn finger	285..305	CDD:275368	7/20 (35%)
		zf-H2C2_2	299..321	CDD:290200	9/25 (36%)
		C2H2 Zn finger	313..333	CDD:275368	6/19 (32%)
		C2H2 Zn finger	341..359	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I8018
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910