DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17802 and CG14710

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	446	Identity:	115/446 - (25%)
Similarity:	190/446 - (42%)	Gaps:	76/446 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QCRLC-GDLIYTQNPVNIFDE--NSKMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQ 65
            |||:| ||...:| .:.:|.:  .|.:.:::.|...:.:....::|...|:.|...::....|||
  Fly     9 QCRICLGDFEESQ-MICLFGDKGESDLRKKLELCCRIRVRQSPQLPEKACNSCCEFVQMWFNFRQ 72

  Fly    66 ACIKTNNRLTIQRRSVEAKDDGCWADPLSDAHEGL-KINDAEVEQEVLYEVSYADNEGLEEDHDL 129
            .|:  |:::             .|....|:..|.| :.:|||. ...|||             :|
  Fly    73 MCL--NSQV-------------YWETSSSERPEALAQASDAEY-MLYLYE-------------NL 108

  Fly   130 YKKEEEESEVNENKEFEDIACEIPFSKEDDEQEQQQEYEDMVDKKTGHDDGEESQECEESQPDEE 194
            :.|...|   |:.||      ||...:|.|||::.|..|  |....|....|..:|.||  |:.|
  Fly   109 HLKLGTE---NQEKE------EITAIEEGDEQQEDQSQE--VLDFNGFIINESIEEDEE--PNTE 160

  Fly   195 ESQQNEEDEEESQEDDDELWQNEDGDSD-----TDADSMSDIEATSRQSALDEDKKPRRKY---- 250
            ..:|......:|..||.::.:..|...:     ::|::..::|....:..:.....|...:
  Fly   161 SPEQILISHMDSYVDDQQMEELIDDKGELVEELSNANTFYEVEYGDEELLMSSAPSPHPSFKMDK 225

  Fly   251 TKRSSPKNDDTDFLKPAKKKRKTYIS-----------QKVHICDHCGKKFTDKGNFNLHVLRHSG 304
            .|...|:..|.:.    |.|||...:           ::..:|..||..|..|..|..|::.||.
  Fly   226 QKPGRPRKPDAEL----KFKRKDINAKERGNQPKCKEEEKFMCILCGNVFYKKSVFTAHMMTHSE 286

  Fly   305 VKPFECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNF 369
            .||.:|..|.:.......|..||| :|.|::||.|.:||..|...:.|.||| |||.|.:.   :
  Fly   287 YKPHQCEICNKSFRQMGELRAHIR-RHTGDRPYKCMYCDRHFYDRSERVRHE-RVHTNTRP---Y 346

  Fly   370 KCNYCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSRQHQNKL 425
            .|..|.|.:........|.:.|:.::|::|.:|..|||....||.|.::..|:||:
  Fly   347 ACQECGKTFTHTAILKNHILSHSAQKNYNCGICCKSFTLLHQLKAHLQTLTHRNKM 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	18/72 (25%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..331	CDD:275368	6/20 (30%)
		C2H2 Zn finger	339..360	CDD:275368	9/20 (45%)
		C2H2 Zn finger	371..388	CDD:275370	3/16 (19%)
		zf-met	398..421	CDD:289631	8/22 (36%)
		C2H2 Zn finger	399..417	CDD:275368	8/17 (47%)
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071	19/89 (21%)
		COG5048	<261..395	CDD:227381	47/138 (34%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		zf-C2H2	290..312	CDD:278523	6/22 (27%)
		C2H2 Zn finger	292..312	CDD:275368	6/20 (30%)
		zf-H2C2_2	304..327	CDD:290200	11/23 (48%)
		C2H2 Zn finger	320..340	CDD:275368	9/20 (45%)
		zf-H2C2_2	335..357	CDD:290200	10/25 (40%)
		C2H2 Zn finger	348..368	CDD:275368	4/19 (21%)
		C2H2 Zn finger	376..395	CDD:275368	8/18 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960