Protein Alignment Nnk and M1BP

DIOPT Version :10

• Sequence 1: NP_650659.2
• Gene: Nnk / 42143
• FlyBaseID: FBgn0038549
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_649825.1
• Gene: M1BP / 41042
• FlyBaseID: FBgn0037621
• Length: 418
• Species: Drosophila melanogaster
• Alignment Length: 452
• Identity: 121/452 - (26%)
• Similarity: 194/452 - (42%)
• Gaps: 76/452 - (16%)

  Fly     5 CRLCGDLIYTQNPVNIFD-ENSKMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQACI 68
            ||:|......:....:|: .|:||:..|..:|||.|.::..:|..:|.||.:.|.||:..|:.||
  Fly    13 CRVCAKYASNKRSPKLFERSNTKMIDNIEALTGLRLENYGCLPDQICECCSMELASAVKLRERCI 77

  Fly    69 KTNNRLTI-----QRRSVEAKDDGCWADPLSDAHEGLKINDAEVEQEVLYEVSYADNEGLEEDHD 128
            .....|.:     ||:.:.|                 ....|.:.::::..|...|      |.:
  Fly    78 AAQRELLLGLTEEQRQGISA-----------------FYRAAVMGEDIVQTVKTPD------DDE 119

  Fly   129 LYKKEEEESEVNENKEFEDIACEIPFSKEDDEQ-EQQQEYEDMVDKKTGHDDGE---ESQECEES 189
            :|            ..:::|..|.|..:.||.: |....|.::.:...|.||..   |..:.:..
  Fly   120 VY------------ATYQEIVLEEPKEEIDDTKVEYDNTYYEVAEGHAGEDDAASLIEEADYDSI 172

  Fly   190 QPDEEESQQNEEDEEESQEDDDELWQNEDGDS---DTDADSMSDIEATSRQSALDEDKKPRRKYT 251
            ..::||.||..|.:|     |.||...:..|:   |      ||.|.....:.||::.:......
  Fly   173 MAEDEEQQQTLELDE-----DTELIVGDVNDAYVYD------SDDEVAVLDNVLDDEYEHENIVV 226

  Fly   252 KRSSPKNDDTDFLKPAKKKRKTYISQK----VHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPE 312
            |:.|        |.|..|.|.....::    |:||:.||.....:..|.||..||.|.|.|.|..
  Fly   227 KKCS--------LPPKPKVRSDDARRRGTGGVYICEQCGNHIKGRMAFELHCRRHRGDKQFGCEL 283

  Fly   313 CGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKR 377
            |..:......|..|:| ||.||:|:||::|...|...|.|.:|| |.|.|::.   :.|..|.|.
  Fly   284 CQSRFCTTSELKRHMR-KHTGERPFACKYCGRCFTDYTTRVKHE-RTHTNERP---YVCGTCGKA 343

  Fly   378 YESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSRQHQNKLIAMSAKSEIDSKNK 439
            :.:.|....|.::|:|||.:.||:|..||...::|.||:||..|:..|.....|..::.:.|
  Fly   344 FTTGYILKNHMLIHSGERAYRCELCDKSFMLPTHLSTHFRSGVHKRHLEKAEMKQVLEQEQK 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nnk	NP_650659.2	zf-AD	4..74	CDD:214871	22/69 (32%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		C2H2 Zn finger	310..331	CDD:275368	5/20 (25%)
		C2H2 Zn finger	339..360	CDD:275368	8/20 (40%)
		C2H2 Zn finger	371..388	CDD:275370	4/16 (25%)
		zf-met	397..421	CDD:463736	10/23 (43%)
		C2H2 Zn finger	399..417	CDD:275368	8/17 (47%)
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871	22/70 (31%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		COG5048	276..>331	CDD:227381	22/56 (39%)
		C2H2 Zn finger	281..301	CDD:275368	5/20 (25%)
		zf-H2C2_2	293..317	CDD:463886	11/24 (46%)
		C2H2 Zn finger	309..329	CDD:275368	8/20 (40%)
		zf-H2C2_2	324..346	CDD:463886	8/25 (32%)
		C2H2 Zn finger	337..357	CDD:275368	5/19 (26%)
		zf-H2C2_2	350..372	CDD:463886	8/21 (38%)
		C2H2 Zn finger	365..383	CDD:275368	8/17 (47%)