DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and ouib

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_649822.2	Gene:	ouib / 41039	FlyBaseID:	FBgn0037618	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	421	Identity:	121/421 - (28%)
Similarity:	172/421 - (40%)	Gaps:	122/421 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRLCGDLIYTQNPVNIFD-ENSKMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQACI 68
            ||:||.....:..:|:|| .|.|.::.:.:::||.|.|...:|..||.||...|:||:|||:.||
  Fly     6 CRVCGRQKICEKSLNLFDLVNRKYLKHLHMISGLRLVDLDDVPGFMCLCCQAELRSALAFRKLCI 70

  Fly    69 KTNNRLTIQRRSVEAKDDGCWADPLSDAHEGLKINDAEVEQEVLYEVSYADNEGLEEDHDLYKKE 133
            ||..:               |          |.|.|              |:...:||
  Fly    71 KTQTK---------------W----------LTIED--------------DSSSGDED------- 89

  Fly   134 EEESEVNENKEFEDIACEIPFSKEDDEQEQQQEYEDMVDKKTGHDDGEESQECEESQPDEEESQQ 198
                 .|:|.|.|...|               .:.|...||.|....|..|...|.:|
  Fly    90 -----TNDNSELESEKC---------------AFSDFGKKKEGELVEETFQVLIEEEP------- 127

  Fly   199 NEEDEEESQEDDDELWQNEDGDSDTDADSMSDIEATSRQSALDEDKKPRRKYTKRSSPKNDDTDF 263
                                    .|.....|.:|..|:..:||...|.:|..|.|: |.||
  Fly   128 ------------------------MDKTLNRDAKAQLREDGIDEKCVPSQKIIKVST-KLDD--- 164

  Fly   264 LKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNRYILNIHIR 328
                          :::||:.||...|.|..|..|:.:|.|.:||.|.:|..:..:...|..|.|
  Fly   165 --------------QIYICELCGTHATSKPTFQRHMRKHRGERPFGCKDCDARFLSAGELRAHHR 215

  Fly   329 VKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRYESNYQRAKHEVVHTG 393
            | |.||:|:||:||::|:|....|..|| |.|.|.:.   :.|..|.|::.:.|....|.|:|||
  Fly   216 V-HTGEQPFACRFCEKRYVSYMGRLIHE-RTHTNDRP---YVCEECGKKFTTAYVLKNHMVIHTG 275

  Fly   394 ERNFHCEVCKVSFTRNSNLKTHYRSRQH-QN 423
            ||||.|::|..||.|.::|.||.||..| ||
  Fly   276 ERNFRCDICDRSFQRKAHLVTHTRSMMHLQN 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	28/69 (41%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..331	CDD:275368	6/20 (30%)
		C2H2 Zn finger	339..360	CDD:275368	9/20 (45%)
		C2H2 Zn finger	371..388	CDD:275370	4/16 (25%)
		zf-met	398..421	CDD:289631	10/22 (45%)
		C2H2 Zn finger	399..417	CDD:275368	8/17 (47%)
ouib	NP_649822.2	zf-AD	5..78	CDD:214871	29/96 (30%)
		COG5048	<158..300	CDD:227381	59/164 (36%)
		C2H2 Zn finger	169..189	CDD:275368	7/19 (37%)
		C2H2 Zn finger	197..217	CDD:275368	6/20 (30%)
		zf-H2C2_2	209..234	CDD:290200	13/25 (52%)
		C2H2 Zn finger	225..245	CDD:275368	9/20 (45%)
		zf-H2C2_2	241..262	CDD:290200	8/24 (33%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		zf-H2C2_2	266..288	CDD:290200	11/21 (52%)
		C2H2 Zn finger	281..299	CDD:275368	8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.860