Protein Alignment Nnk and Zif

DIOPT Version :10

• Sequence 1: NP_650659.2
• Gene: Nnk / 42143
• FlyBaseID: FBgn0038549
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_649657.1
• Gene: Zif / 40795
• FlyBaseID: FBgn0037446
• Length: 388
• Species: Drosophila melanogaster
• Alignment Length: 452
• Identity: 111/452 - (24%)
• Similarity: 181/452 - (40%)
• Gaps: 101/452 - (22%)

  Fly     1 MTPQ-CRLC---GDLIYTQNPVNIFDENS--KMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKS 59
            :||| ||:|   .:.:...:.:....|.|  :|:.|:..|:...|.|...:|..:|..|.:.|..
  Fly     5 LTPQTCRVCLAQSERLQRLDEIREEGEESPNEMLIQLLGVSYSNLNDREHIPDGICKSCKVELNM 69

  Fly    60 AIAFRQACIKTNNRLTIQRRSVEAKDDGCWADPLSDAHEGLKINDAEVEQEVLYEVSYADNEGLE 124
            |..||:..::                                 ...|:|:       |....||.
  Fly    70 AYQFREKALR---------------------------------KQMEIEE-------YCRELGLL 94

  Fly   125 EDHDLYKKEEEESEVNENKEFEDIACEIPFSKEDDEQEQQ--QEYEDMVDKKTGHDDGEESQECE 187
            ::.|                       :...||:|..:||  :|...:.:..||.::.:|.:..|
  Fly    95 DESD-----------------------VMMIKEEDGSQQQCDEEMYILEETTTGEEEHQEEKGHE 136

  Fly   188 E-SQPDEEESQQNEEDEEESQEDDDELWQNEDGDSDTDADSMSDIEAT-SRQSALDE----DKKP 246
            | .:.|..:.|:...|..|..||:..:..|.| .::...:|....|.| |:|.||.|    ..|.
  Fly   137 EYLEVDTSDQQECIGDTIEYLEDNYTIEMNSD-QTEIVLESEKQYEETPSQQLALQEAAKASLKA 200

  Fly   247 RRKYTKR---SSPKNDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPF 308
            ||...:|   |...:|.|:              :..:|||.||..:..:|....|..||.|:..:
  Fly   201 RRGRVRRGLNSLTTSDGTE--------------KGGYICDVCGNFYEKRGRMMEHRRRHDGICQY 251

  Fly   309 ECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNY 373
            .|..|..|...|..|..|: ..|.|.|||.|.||..:|.:.::...||| |||..|.   :.|..
  Fly   252 ACELCDAKFQVREQLRKHM-YSHTGSKPYKCSFCSRQFFYESVLKSHEN-VHRGIKP---YVCKV 311

  Fly   374 CDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSRQHQNK-LIAMSAKSEI 434
            |||.:...:...|||::|:..:.:.|:.|...|....:::.|..::.|||. ::|.|.|.|:
  Fly   312 CDKAFAYAHSLTKHELIHSDIKLYRCDYCNKDFRLLHHMRQHEETKLHQNAVMLAESMKVEM 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nnk	NP_650659.2	zf-AD	4..74	CDD:214871	18/75 (24%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		C2H2 Zn finger	310..331	CDD:275368	6/20 (30%)
		C2H2 Zn finger	339..360	CDD:275368	7/20 (35%)
		C2H2 Zn finger	371..388	CDD:275370	5/16 (31%)
		zf-met	397..421	CDD:463736	4/23 (17%)
		C2H2 Zn finger	399..417	CDD:275368	4/17 (24%)
Zif	NP_649657.1	zf-AD	9..87	CDD:462262	19/117 (16%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		COG5048	<250..369	CDD:227381	38/123 (31%)
		C2H2 Zn finger	253..273	CDD:275368	6/20 (30%)
		C2H2 Zn finger	281..301	CDD:275368	7/20 (35%)
		C2H2 Zn finger	309..329	CDD:275368	7/19 (37%)
		C2H2 Zn finger	337..353	CDD:275368	3/15 (20%)