DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and ZNF829

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001165450.1	Gene:	ZNF829 / 374899	HGNCID:	34032	Length:	513	Species:	Homo sapiens

Alignment Length:	188	Identity:	57/188 - (30%)
Similarity:	91/188 - (48%)	Gaps:	20/188 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 SRQSALDEDKKPRR-----KYTKRSSPKNDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGN 294
            |:...:...:||..     |..|..|..||          .::.:..:|.:.|..|||.||....
Human   309 SQHQRIHTGEKPYECKECGKAFKYCSNLND----------HQRIHTGEKPYECKVCGKAFTKSSQ 363

  Fly   295 FNLHVLRHSGVKPFECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRV 359
            ..||:..|:|.||:||.||| |.|.::...|..:..|.|||||.|:.|.:.|..::..:.| :|:
Human   364 LFLHLRIHTGEKPYECKECG-KAFTQHSRLIQHQRMHTGEKPYECKQCGKAFNSASTLTNH-HRI 426

  Fly   360 HRNKKTPKNFKCNYCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYR 417
            |..:|.   ::|..|.|.:..:.:..:|:.:||.|:.:.|..|..:|.:.|||..|.|
Human   427 HAGEKL---YECEECRKAFIQSSELIQHQRIHTDEKPYECNECGKAFNKGSNLTRHQR 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		C2H2 Zn finger	310..331	CDD:275368	7/20 (35%)
		C2H2 Zn finger	339..360	CDD:275368	5/20 (25%)
		C2H2 Zn finger	371..388	CDD:275370	3/16 (19%)
		zf-met	398..421	CDD:289631	8/20 (40%)
		C2H2 Zn finger	399..417	CDD:275368	7/17 (41%)
ZNF829	NP_001165450.1	KRAB	116..176	CDD:214630
		KRAB	116..155	CDD:279668
		COG5048	<149..425	CDD:227381	39/127 (31%)
		zf-C2H2	238..259	CDD:278523
		C2H2 Zn finger	239..259	CDD:275368
		C2H2 Zn finger	271..287	CDD:275368
		zf-H2C2_2	282..304	CDD:290200
		C2H2 Zn finger	295..315	CDD:275368	1/5 (20%)
		zf-H2C2_2	307..332	CDD:290200	4/22 (18%)
		C2H2 Zn finger	323..343	CDD:275368	5/29 (17%)
		zf-H2C2_2	335..359	CDD:290200	7/33 (21%)
		C2H2 Zn finger	351..371	CDD:275368	8/19 (42%)
		zf-H2C2_2	367..388	CDD:290200	12/21 (57%)
		C2H2 Zn finger	379..399	CDD:275368	7/20 (35%)
		zf-H2C2_2	392..416	CDD:290200	10/23 (43%)
		C2H2 Zn finger	407..427	CDD:275368	5/20 (25%)
		C2H2 Zn finger	435..455	CDD:275368	4/19 (21%)
		zf-H2C2_2	447..471	CDD:290200	6/23 (26%)
		C2H2 Zn finger	463..483	CDD:275368	8/19 (42%)
		zf-H2C2_2	475..498	CDD:290200	4/7 (57%)
		C2H2 Zn finger	491..511	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960