DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17802 and CG10321

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	98/432 - (22%)
Similarity:	160/432 - (37%)	Gaps:	120/432 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 HEGLKINDAEVEQEVLYEVSYADNEGLEEDHDLYKKEEEESEVNENKEFEDIAC----EIPFSKE 157
            |.|..:.||:|  ::|.:....::|.||   |:|    |:.:...:..||.|..    :..|.|:
  Fly   322 HVGASLGDADV--QLLEDGCEVEDEELE---DVY----EQLDSKADHSFETIVLDDDQQQDFLKD 377

  Fly   158 DDEQEQQQEYEDMVDKKT-GH---DDGEESQECEESQPDEEESQQNEEDE-----EESQEDDDEL 213
            ..|..|....||:...:: .|   ||.::.|..:|.: ||||..:.|||:     ||.|.:|||:
  Fly   378 HHEHHQVMINEDLTQSESQDHEYFDDLDQQQAMDEIE-DEEEQMKPEEDQDTFIIEEIQLEDDEM 441

  Fly   214 WQNEDGD------------------SDTDAD-SMSDIEATSRQSALDEDK----------KPRRK 249
            ..:.||:                  .|.|.| ..|.:|....::::|.|:          :..::
  Fly   442 LDDPDGEEIDQDCEYIGEEQDPHLSGDVDDDLEYSIMEPPDGETSVDIDQAFMDSEQSHHQQHQE 506

  Fly   250 YTKRSSPKNDDTDFLK---------------------PAKKKRKTY-ISQKVHI--CDH----CG 286
            ..:..|.:|...:|.:                     |.:.||..: |...|.:  |||    .|
  Fly   507 EMQSISLENAVVEFSQATTTTEALVGPTMTVSSASPTPKRAKRSNHQIPAGVTLEPCDHQPPAAG 571

  Fly   287 KKFTDK---GNFNLHVLRHSGVKPFECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCDERF-- 346
            ...:.|   .|....|...|.:......:..:.:.|.....|.......|...|.|..|...|
  Fly   572 STTSSKLAAANSRQLVQTASVIAAAGADDNYEIDANLVTEFIRQHTSPLGSGRYICHLCSTEFRQ 636

  Fly   347 ---VHSTMRSRHENRVHRN-KKTP------KNFK--------------------CNYCDKRYESN 381
               :.:.|.| |.|.:..| ||.|      |:||                    |..|::.::|.
  Fly   637 FKGLQNHMHS-HTNWIRANCKKQPQCQICLKSFKGPGMLRMHMKTHDAESSTPMCTICNRTFKSK 700

  Fly   382 YQRAKHEVVHTGERNFHCEV--CKVSFTRNSNLKTHYRSRQH 421
            ....:|...|. :|.:.|.|  |:.:|:...|||.|. .|:|
  Fly   701 AILYRHRQTHQ-QRAYCCGVANCRKNFSSAVNLKWHV-ERKH 740

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	7/26 (27%)
		C2H2 Zn finger	310..331	CDD:275368	2/20 (10%)
		C2H2 Zn finger	339..360	CDD:275368	7/25 (28%)
		C2H2 Zn finger	371..388	CDD:275370	3/16 (19%)
		zf-met	398..421	CDD:289631	9/24 (38%)
		C2H2 Zn finger	399..417	CDD:275368	8/19 (42%)
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562	25/111 (23%)
		C2H2 Zn finger	627..647	CDD:275368	5/20 (25%)
		C2H2 Zn finger	661..681	CDD:275368	3/19 (16%)
		C2H2 Zn finger	690..710	CDD:275368	4/19 (21%)
		C2H2 Zn finger	717..740	CDD:275368	9/23 (39%)
		C2H2 Zn finger	750..767	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000