DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and ZNF517

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001371833.1	Gene:	ZNF517 / 340385	HGNCID:	27984	Length:	492	Species:	Homo sapiens

Alignment Length:	166	Identity:	50/166 - (30%)
Similarity:	75/166 - (45%)	Gaps:	22/166 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 KTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNRYILNIHIRVKHRGEKP 336
            :.:..::.:.|..|||.|:.......|...|:|.|||.|.|||:....|:.||.|.|: |.||:|
Human   253 RVHTRERPYACGECGKAFSRSSRLLQHQKFHTGEKPFACTECGKAFCRRFTLNEHGRI-HSGERP 316

  Fly   337 YACQFCDERFVHSTMRSRHENRVH--------------------RNKKTPKNFKCNYCDKRYESN 381
            |.|..|.:||:..:...:| :|:|                    |.:......:|..|.:.:..|
Human   317 YRCLRCGQRFIRGSSLLKH-HRLHAQEGAQDGGVGQGALLGAAQRPQAGDPPHECPVCGRPFRHN 380

  Fly   382 YQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYR 417
            .....|..:||||:.|.|..|..:|.|.|||..|.:
Human   381 SLLLLHLRLHTGEKPFECAECGKAFGRKSNLTLHQK 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		C2H2 Zn finger	310..331	CDD:275368	9/20 (45%)
		C2H2 Zn finger	339..360	CDD:275368	6/20 (30%)
		C2H2 Zn finger	371..388	CDD:275370	3/16 (19%)
		zf-met	398..421	CDD:289631	8/20 (40%)
		C2H2 Zn finger	399..417	CDD:275368	8/17 (47%)
ZNF517	NP_001371833.1	KRAB	14..73	CDD:214630
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	129..170
		C2H2 Zn finger	180..199	CDD:275368
		COG5048	<203..342	CDD:227381	32/90 (36%)
		C2H2 Zn finger	207..227	CDD:275368
		C2H2 Zn finger	235..255	CDD:275368	0/1 (0%)
		C2H2 Zn finger	263..283	CDD:275368	6/19 (32%)
		COG5048	<287..459	CDD:227381	42/132 (32%)
		C2H2 Zn finger	291..311	CDD:275368	9/20 (45%)
		C2H2 Zn finger	319..339	CDD:275368	6/20 (30%)
		C2H2 Zn finger	370..390	CDD:275368	4/19 (21%)
		C2H2 Zn finger	398..418	CDD:275368	8/19 (42%)
		C2H2 Zn finger	426..446	CDD:275368
		C2H2 Zn finger	454..474	CDD:275368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	472..492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050