DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17802 and CG31441

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	114/449 - (25%)
Similarity:	184/449 - (40%)	Gaps:	139/449 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRLCGDLIYTQNPVNIFDENSKMVRQ--------IALVTGLWLTDHSKMPRNMCSCCLLSLKSAI 61
            ||.||     :|..|:....:|:..:        :..:|.::|...:.:|..:|.||.:.|...:
  Fly     8 CRTCG-----KNVTNLQGRATKLFNKSNYHFISILENITDMYLEFDTTLPHLICQCCKVQLDRIL 67

  Fly    62 AFRQACIKTN------NRLTIQRRSVEAKDDGCWADPLSDAHEGLKINDAEVEQEVLYE------ 114
            .||..|::.:      ||..::::::              ..|.|...|.|..|:.|::
  Fly    68 TFRNKCLEVHKSFMAANRKLLRKKAI--------------VDEELDKPDVEKLQQDLWDHTDQEM 118

  Fly   115 -VSYADNEG-LEEDHDLYKKEEEESEVNENKEFEDIACEIPFSKEDDEQEQQQEYEDMVDKKTGH 177
             |:.||..| |.|||            |:|::.:|         .:|..:.::..|:.|..:|
  Fly   119 CVAMADTAGLLREDH------------NDNEKAKD---------AEDATQNEKNQEEQVQVQT-- 160

  Fly   178 DDGEESQECEESQPDEEESQQNEEDEEESQEDDDELWQNEDGDSDTDADSMSDIEATSRQSALDE 242
               ||.:.|:|                                   ...:||.|  :...||
  Fly   161 ---EEVEHCQE-----------------------------------QLHNMSII--SKGVSA--- 182

  Fly   243 DKKPRRKYTKRSSPKNDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKP 307
             :.|:|  |||:|                      |...||.||..|.......||:.||||.||
  Fly   183 -RVPKR--TKRNS----------------------KSWFCDQCGGVFKSSTYLKLHLQRHSGHKP 222

  Fly   308 FECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCN 372
            |.|..|..|.:....:..| |:.|...:||||:||.:.:...:.:..|| |.|.|::.   |:|.
  Fly   223 FACDICQAKYYTDNEMRRH-RILHTDARPYACRFCSKTYRGCSSKVVHE-RTHTNERP---FQCQ 282

  Fly   373 YCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSRQHQNKLIAMSAK 431
            :|||.:.|...|.|||::||.:|.:|||:|...|.|:|:|..|..::.||.:  |.||:
  Fly   283 HCDKAFTSTSTRQKHEMLHTNQRKYHCEICDQWFLRSSHLTLHQSTKLHQRR--AESAR 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	18/82 (22%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..331	CDD:275368	5/20 (25%)
		C2H2 Zn finger	339..360	CDD:275368	6/20 (30%)
		C2H2 Zn finger	371..388	CDD:275370	7/16 (44%)
		zf-met	398..421	CDD:289631	9/22 (41%)
		C2H2 Zn finger	399..417	CDD:275368	8/17 (47%)
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	17/78 (22%)
		COG5048	<174..337	CDD:227381	67/199 (34%)
		C2H2 Zn finger	197..217	CDD:275370	7/19 (37%)
		C2H2 Zn finger	225..245	CDD:275368	5/20 (25%)
		C2H2 Zn finger	253..273	CDD:275368	6/20 (30%)
		zf-H2C2_2	268..290	CDD:290200	10/25 (40%)
		C2H2 Zn finger	281..301	CDD:275368	9/19 (47%)
		C2H2 Zn finger	309..328	CDD:275368	8/18 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950