DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and ZNF621

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001091884.1	Gene:	ZNF621 / 285268	HGNCID:	24787	Length:	439	Species:	Homo sapiens

Alignment Length:	154	Identity:	49/154 - (31%)
Similarity:	75/154 - (48%)	Gaps:	11/154 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 KKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNRYILNIHIRVKHRG 333
            :.:.::..:|...|..|||.|....:..:|...|.|..|:||.|||:...:...|..|.|: |.|
Human   168 RHQMSHTGEKPFKCKECGKAFKSSYDCIVHEKNHIGEGPYECKECGKGLSSNTALTQHQRI-HTG 231

  Fly   334 EKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRYESNYQRAKHEVVHTGERNFH 398
            ||||.|:.|.:.|..|....:|: |:|..:|.   :||..|.|.:........|:.:||||:.:.
Human   232 EKPYECKECGKAFRRSAAYLQHQ-RLHTGEKL---YKCKECWKAFGCRSLFIVHQRIHTGEKPYQ 292

  Fly   399 CEVCKVSFTRNSNLKTHYRSRQHQ 422
            |:.|..:||:.      ..|.|||
Human   293 CKECGKAFTQK------IASIQHQ 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		C2H2 Zn finger	310..331	CDD:275368	7/20 (35%)
		C2H2 Zn finger	339..360	CDD:275368	6/20 (30%)
		C2H2 Zn finger	371..388	CDD:275370	3/16 (19%)
		zf-met	398..421	CDD:289631	5/22 (23%)
		C2H2 Zn finger	399..417	CDD:275368	4/17 (24%)
ZNF621	NP_001091884.1	KRAB	11..71	CDD:214630
		COG4049	145..198	CDD:226535	6/29 (21%)
		C2H2 Zn finger	153..173	CDD:275368	0/4 (0%)
		zf-H2C2_2	166..190	CDD:316026	6/21 (29%)
		C2H2 Zn finger	209..229	CDD:275368	7/20 (35%)
		zf-H2C2_2	221..246	CDD:316026	12/25 (48%)
		C2H2 Zn finger	237..257	CDD:275368	6/20 (30%)
		C2H2 Zn finger	265..285	CDD:275368	4/19 (21%)
		zf-H2C2_2	281..302	CDD:316026	8/20 (40%)
		C2H2 Zn finger	293..313	CDD:275368	8/24 (33%)
		zf-H2C2_2	308..329	CDD:316026	3/3 (100%)
		C2H2 Zn finger	321..341	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050