DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and ZNF844

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_016882153.1	Gene:	ZNF844 / 284391	HGNCID:	25932	Length:	668	Species:	Homo sapiens

Alignment Length:	317	Identity:	76/317 - (23%)
Similarity:	132/317 - (41%)	Gaps:	55/317 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 FEDIACEIPFSKED---DEQEQQQEYEDMVDK------KTGHDDGEESQECEESQPD-------- 192
            |||:|  :.|::|:   .:..|:..|.:::.:      ..|....:::.|.:...|.
Human     8 FEDVA--VNFTQEEWSLLDPSQKNLYREVMQETLRNLASIGEKWKDQNIEDQYKNPRNNLRSLLG 70

  Fly   193 ---EEESQQNEEDEEESQEDDDEL-WQNEDGDSDTDADSMSDI----EATSRQSALDEDKKP--- 246
               :|.:::|...|..||..||.| .:...|....::....::    .:.:|....|...||
Human    71 ERVDENTEENHCGETSSQIPDDTLNKKTSPGVKSCESSVCGEVFVGHSSLNRHIRADTAHKPSEY 135

  Fly   247 -----------RRKYTKRSSPKNDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVL 300
                       :||...|..|.         .:.:.|.:..:|::.|..|||.|....:...|::
Human   136 QEYGQEPYKCQQRKKAFRCHPS---------FQMQEKAHTGEKLYDCKECGKTFISHSSIQRHMI 191

  Fly   301 RHSGVKPFECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKT 365
            .|:|...::|..||:......|..||.|| |.|||||.|:.|.:.|.:||....|| |.|..:|.
Human   192 MHNGDGTYKCKFCGKACPCLSIYLIHERV-HTGEKPYKCKQCGKAFSYSTSLQIHE-RTHTGEKP 254

  Fly   366 PKNFKCNYCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSRQHQ 422
               ::|..|.|.:.|.....:|...||||:.:.|:.|..:|....:.:.|.|:...:
Human   255 ---YECKECGKAFGSPNSLYEHRRTHTGEKPYECKQCGKAFRWFHSFQIHERTHSEE 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		C2H2 Zn finger	310..331	CDD:275368	8/20 (40%)
		C2H2 Zn finger	339..360	CDD:275368	8/20 (40%)
		C2H2 Zn finger	371..388	CDD:275370	4/16 (25%)
		zf-met	398..421	CDD:289631	5/22 (23%)
		C2H2 Zn finger	399..417	CDD:275368	4/17 (24%)
ZNF844	XP_016882153.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050