DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and ZNF620

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_016861553.1	Gene:	ZNF620 / 253639	HGNCID:	28742	Length:	467	Species:	Homo sapiens

Alignment Length:	472	Identity:	103/472 - (21%)
Similarity:	166/472 - (35%)	Gaps:	169/472 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 RQACI--------KTNNRLTIQRRSVEAKDDGCWADPLSDAHE----GLKINDAEVEQE-VLYE- 114
            ||.|:        |.::||.:.:         ||    ...||    .|:.:.|.|..| |.:|
Human     9 RQGCLGSSQTPRCKPSSRLHLPK---------CW----DYRHEPPCLALQFSLANVVMEPVTFED 60

  Fly   115 --VSYADNEGLEED---HDLYKKEEEESEVNENKEFEDIAC-----------------EIPFSKE 157
              |.:..||....|   ..||::...|:..|       :|.                 |:|:..:
Human    61 VAVYFTQNEWASLDSVQRALYREVMLENYAN-------VASLAFPFTTPVLVSQLEQGELPWGLD 118

  Fly   158 ---------------DDEQEQQQE---YEDMVDKKT-------GHDDGEESQECE----ESQPD- 192
                           .||...::|   .:|.|.|:|       |...|..||..:    ..||.
Human   119 PWEPMGREALRGICPGDEARTEKEGLTPKDHVSKETESFRLMVGGLPGNVSQHLDFGSSLEQPQG 183

  Fly   193 --------------EEESQQNEEDEEESQEDDDELWQNEDGDSDTDADSMSDIEATSRQSALDED 243
                          :..::.:|..|.::.|..::|.:|              |..:::.:
Human   184 HWIIKTKSKRRHFTDTSARHHEAYEVKNGEKFEKLGKN--------------ISVSTQLT----- 229

  Fly   244 KKPRRKYTKRSSPKNDDT--------------DFLKPAKKKRKTYISQKVHICDHCGKKFTDKGN 294
                   |.:::|....:              ||    .:..|.:..:|...|..|||.|.....
Human   230 -------TNQTNPSGQISYECGQCGRYFIQMADF----HRHEKCHTGEKSFECKECGKYFRYNSL 283

  Fly   295 FNLHVLRHSGVKPFECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHEN-- 357
            ...|.:.|:|.|||:|.|||:...:...|..|.|: |.|||||.|:.|.:.|..|::..:|:.
Human   284 LIRHQIIHTGKKPFKCKECGKGLSSDTALIQHQRI-HTGEKPYECKECGKAFSSSSVFLQHQRFH 347

  Fly   358 ---------------------RVHRNKKT-PKNFKCNYCDKRYESNYQRAKHEVVHTGERNFHCE 400
                                 .||:...| .|.::|..|.||..||....:|:.:||||:.|.|:
Human   348 TGEKLYECNECWKTFSCSSSFTVHQRMHTGEKPYECKECGKRLSSNTALTQHQRIHTGEKPFECK 412

  Fly   401 VCKVSFTRNSNLKTHYR 417
            .|..:|.:...|..|.|
Human   413 ECGKAFNQKITLIQHQR 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	4/17 (24%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		C2H2 Zn finger	310..331	CDD:275368	7/20 (35%)
		C2H2 Zn finger	339..360	CDD:275368	5/43 (12%)
		C2H2 Zn finger	371..388	CDD:275370	6/16 (38%)
		zf-met	398..421	CDD:289631	6/20 (30%)
		C2H2 Zn finger	399..417	CDD:275368	5/17 (29%)
ZNF620	XP_016861553.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050