Protein Alignment CG17802 and ZNF281

DIOPT Version :9

• Sequence 1: NP_650659.2
• Gene: CG17802 / 42143
• FlyBaseID: FBgn0038549
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_001268222.1
• Gene: ZNF281 / 23528
• HGNCID: 13075
• Length: 895
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 74/330 - (22%)
• Similarity: 113/330 - (34%)
• Gaps: 101/330 - (30%)

  Fly   156 KEDDEQEQQQEYEDMVDKKTGHDDGEESQECEESQPD----------------------EEESQQ 198
            |..|.:|||..:.     ...|..|......||..|.                      :::..|
Human   131 KPADPEEQQSHHH-----HHHHHYGGLFAGAEERSPGLGGGEGGSHGVIQDLSILHQHVQQQPAQ 190

  Fly   199 NEED---EEESQEDDDELWQNEDGDSDTDADSMSDIEATSRQSALDEDKKPRRKYTKRSSPK--- 257
            :..|   ...|:.||..  ..|:...||      :::...|.....:..|.:||.:..|.|.
Human   191 HHRDVLLSSSSRTDDHH--GTEEPKQDT------NVKKAKRPKPESQGIKAKRKPSASSKPSLVG 247

  Fly   258 NDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNRYI 322
            :.:...|.|         |||.||||||...|....:...|||.|:|.:||:|.:|......:|:
Human   248 DGEGAILSP---------SQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYL 303

  Fly   323 LNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRYESNYQRAKH 387
            |..|.:: |..|||:.|..|..:|:                                ..|...:|
Human   304 LQRHEKI-HSREKPFGCDQCSMKFI--------------------------------QKYHMERH 335

  Fly   388 EVVHTGERNFHCEVCKVSFTRNSNLKTHYR----------------SRQHQN--KLIAMSAKSEI 434
            :..|:||:.:.|:.|:..|:|...|..|.|                |..|.|  .|..:|..:..
Human   336 KRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEVIVKGATSAEPGSSNHTNMGNLAVLSQGNTS 400

  Fly   435 DSKNK 439
            .|:.|
Human   401 SSRRK 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		C2H2 Zn finger	310..331	CDD:275368	5/20 (25%)
		C2H2 Zn finger	339..360	CDD:275368	3/20 (15%)
		C2H2 Zn finger	371..388	CDD:275370	1/16 (6%)
		zf-met	398..421	CDD:289631	8/38 (21%)
		C2H2 Zn finger	399..417	CDD:275368	6/17 (35%)
ZNF281	NP_001268222.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..113
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	130..149		6/22 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	183..253		14/77 (18%)
		C2H2 Zn finger	263..283	CDD:275368	8/19 (42%)
		zf-H2C2_2	275..300	CDD:316026	9/24 (38%)
		C2H2 Zn finger	291..311	CDD:275368	5/20 (25%)
		zf-H2C2_2	304..328	CDD:316026	9/56 (16%)
		C2H2 Zn finger	319..339	CDD:275368	5/51 (10%)
		zf-H2C2_2	331..356	CDD:316026	7/24 (29%)
		C2H2 Zn finger	347..366	CDD:275368	6/18 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	377..427		7/29 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	638..660
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	778..817

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910