DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and ZSCAN23

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001012458.1	Gene:	ZSCAN23 / 222696	HGNCID:	21193	Length:	389	Species:	Homo sapiens

Alignment Length:	376	Identity:	97/376 - (25%)
Similarity:	154/376 - (40%)	Gaps:	70/376 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 FRQACIKTNNRLTIQRRSVEAKDDGC--WADPLSDAHEGLKINDAEVEQEVLYEVSYADNEGLEE 125
            |||.|.:.:..   .|.:::...:.|  |..|  :.|...:|.:..|.::.|
Human    51 FRQFCYQESPG---PREALQRLQELCHQWLRP--EMHTKEQILELLVLEQFL------------- 97

  Fly   126 DHDLYKKEEEESEVNENKE---------FEDIACEIPFSKEDDEQEQ----QQEYEDMVDKKTGH 177
               ....||.::.|.:::.         .||:..|:     ||..||    ..|.|:.|.:|...
Human    98 ---TILPEELQAWVRQHRPVSGEEAVTVLEDLEREL-----DDPGEQVLSHAHEQEEFVKEKATP 154

  Fly   178 DDGEESQECEESQPDEEESQQNEEDEEESQEDDDE--LWQNEDGDSDTDADSMSDIEATSRQSAL 240
            ...:||.. ::.|..||:...|..:....||.|.:  .|               ::|...::...
Human   155 GAAQESSN-DQFQTLEEQLGYNLREVCPVQEIDGKAGTW---------------NVELAPKREIS 203

  Fly   241 DEDKKPRRKYTKRSS-----PKNDDT-DFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHV 299
            .|.|...:...|::.     |:..|| |.....:|:|.:...::.:||..|||.||.......|.
Human   204 QEVKSLIQVLGKQNGNITQIPEYGDTCDREGRLEKQRVSSSVERPYICSECGKSFTQNSILIEHQ 268

  Fly   300 LRHSGVKPFECPECGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKK 364
            ..|:|.||:||.|||:....|..|..|.|: |.|||.|.|..|.:.|..:. ...|..|:|..:|
Human   269 RTHTGEKPYECDECGRAFSQRSGLFQHQRL-HTGEKRYQCSVCGKAFSQNA-GLFHHLRIHTGEK 331

  Fly   365 TPKNFKCNYCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTH 415
            .   ::||.|:|.:.......||:.:|||||.:.||.|..:|..:.||..|
Human   332 P---YQCNQCNKSFSRRSVLIKHQRIHTGERPYECEECGKNFIYHCNLIQH 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	4/10 (40%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..331	CDD:275368	8/20 (40%)
		C2H2 Zn finger	339..360	CDD:275368	5/20 (25%)
		C2H2 Zn finger	371..388	CDD:275370	5/16 (31%)
		zf-met	398..421	CDD:289631	7/18 (39%)
		C2H2 Zn finger	399..417	CDD:275368	7/17 (41%)
ZSCAN23	NP_001012458.1	SCAN	44..156	CDD:128708	26/130 (20%)
		SCAN	45..132	CDD:280241	18/106 (17%)
		COG5048	<215..384	CDD:227381	58/170 (34%)
		zf-C2H2	249..271	CDD:278523	8/21 (38%)
		C2H2 Zn finger	251..271	CDD:275368	7/19 (37%)
		zf-H2C2_2	264..288	CDD:290200	10/23 (43%)
		C2H2 Zn finger	279..299	CDD:275368	8/20 (40%)
		zf-H2C2_2	292..316	CDD:290200	11/24 (46%)
		C2H2 Zn finger	307..327	CDD:275368	5/20 (25%)
		zf-H2C2_2	323..344	CDD:290200	7/23 (30%)
		C2H2 Zn finger	335..355	CDD:275368	6/19 (32%)
		zf-H2C2_2	348..372	CDD:290200	11/23 (48%)
		C2H2 Zn finger	363..383	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960