DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17802 and ZNF449

DIOPT Version :9

Sequence 1:NP_650659.2 Gene:CG17802 / 42143 FlyBaseID:FBgn0038549 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_689908.3 Gene:ZNF449 / 203523 HGNCID:21039 Length:518 Species:Homo sapiens


Alignment Length:308 Identity:87/308 - (28%)
Similarity:126/308 - (40%) Gaps:52/308 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   141 ENKEFEDIACEIP-----FSKEDDEQ------EQQQEYEDMVDKKTGHDDGEESQECEESQPDEE 194
            |.:.|.|....:|     ||.|:.|:      :..:|.:.::|.|.|.:.|.|::|....|...|
Human   179 ECQNFLDPGYPLPKLDMNFSLENREEPWVKELQDSKEMKQLLDSKIGFEIGIENEEDTSKQKKME 243

  Fly   195 ES-------QQNEEDEEESQEDDDEL---WQNEDGDSDTDADSMSD-----IEATSRQSALDEDK 244
            ..       :.|.......|:|..:|   |:....|..||...:.|     :..|...|.|:|..
Human   244 TMYPFIVTLEGNALQGPILQKDYVQLENQWETPPEDLQTDLAKLVDQQNPTLGETPENSNLEEPL 308

  Fly   245 KPRRKYTKRSSPKNDDTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFE 309
            .|                  ||.|||..   .:|.|.|..|||.|..|.....|...|||.:|.:
Human   309 NP------------------KPHKKKSP---GEKPHRCPQCGKCFARKSQLTGHQRIHSGEEPHK 352

  Fly   310 CPECGQKEFNRYILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYC 374
            |||||::......|..|.|: |.||:||.|..|.:||...:....|: |.|..::|   :||..|
Human   353 CPECGKRFLRSSDLYRHQRL-HTGERPYECTVCKKRFTRRSHLIGHQ-RTHSEEET---YKCLEC 412

  Fly   375 DKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSRQHQ 422
            .|.:.......:|...||||:...|..|..||:|.:.|..|.|:...:
Human   413 GKSFCHGSSLKRHLKTHTGEKPHRCHNCGKSFSRLTALTLHQRTHTEE 460

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17802NP_650659.2 zf-AD 4..74 CDD:285071
C2H2 Zn finger 282..302 CDD:275368 7/19 (37%)
C2H2 Zn finger 310..331 CDD:275368 8/20 (40%)
C2H2 Zn finger 339..360 CDD:275368 6/20 (30%)
C2H2 Zn finger 371..388 CDD:275370 3/16 (19%)
zf-met 398..421 CDD:289631 8/22 (36%)
C2H2 Zn finger 399..417 CDD:275368 7/17 (41%)
ZNF449NP_689908.3 SCAN 27..134 CDD:322011
SFP1 <235..402 CDD:227516 53/189 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 292..325 12/53 (23%)
COG5048 <321..483 CDD:227381 51/145 (35%)
C2H2 Zn finger 325..345 CDD:275368 7/19 (37%)
C2H2 Zn finger 353..373 CDD:275368 8/20 (40%)
C2H2 Zn finger 381..401 CDD:275368 6/20 (30%)
C2H2 Zn finger 409..429 CDD:275368 4/19 (21%)
C2H2 Zn finger 437..457 CDD:275368 8/19 (42%)
C2H2 Zn finger 465..485 CDD:275368
zf-H2C2_2 477..502 CDD:316026
C2H2 Zn finger 493..513 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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