DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17802 and zfp-2

DIOPT Version :9

Sequence 1:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_496055.1	Gene:	zfp-2 / 174505	WormBaseID:	WBGene00009448	Length:	422	Species:	Caenorhabditis elegans

Alignment Length:	331	Identity:	64/331 - (19%)
Similarity:	118/331 - (35%)	Gaps:	75/331 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 QQQEYEDMVDKKTGHDDGEESQECEESQPDEEESQQNEEDEEESQEDDDELWQNE-DGDSDTDAD 226
            ||:.:::  :|..|::  ..:.:|.::....:::...:.::..:.:|..|....| ||:...:..
Worm    31 QQRSWDE--EKPIGYE--LTNTKCYKTPNGVQKTATIQREQLSTSKDFGEQQIVEMDGEFSIEGT 91

  Fly   227 SMSDIEATSRQSALDEDKKP----------RRKYTK----------------RSSPKNDDTDFLK 265
            .|..|..||..........|          ||...|                ..:|.:....::.
Worm    92 DMHAIPCTSSSMQPSTSSNPSSGEHQPVPLRRMAIKIGQRVLRFKVISAEEAPEAPLDTQDSWIN 156

  Fly   266 PAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLR-HSGVKPFECPECGQKEFNRYILNIHIRV 329
            ..|..........::.|.:|...|.:|..:..|:.. |...:||.|..||.:..|:..:..|::
Worm   157 DPKPVTTPKALAGLYRCTNCKTYFGNKEVYQRHIQEVHGDARPFRCFNCGMRFANKTSMTHHLK- 220

  Fly   330 KHRGEKP-YACQFCDERFVHSTMRSRHEN---------------------RVHRNKKTPKNF--- 369
            .|...|| ::|.:|...|.....::||..                     |.|::...|..|
Worm   221 DHSLLKPMFSCDYCPRIFSKLESKTRHHKMHFTRSTCQTCMRFFTTEDALRHHQSTAHPATFDSG 285

  Fly   370 ---------------KCNYCDKRYESNYQRAKHEVVHTGERNFHCEVCKVSFTRNSNLKTHYRSR 419
                           .|:||:.|:........||.:||||:.:.|..|..||.::..|..|.|:
Worm   286 PPPEDLLPNGKSARYSCSYCNLRFHFKKDMLVHERIHTGEKPYSCGYCMKSFAQSQALTAHIRT- 349

  Fly   420 QHQNKL 425
             |..:|
Worm   350 -HTKEL 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071
		C2H2 Zn finger	282..302	CDD:275368	5/20 (25%)
		C2H2 Zn finger	310..331	CDD:275368	5/20 (25%)
		C2H2 Zn finger	339..360	CDD:275368	6/41 (15%)
		C2H2 Zn finger	371..388	CDD:275370	4/16 (25%)
		zf-met	398..421	CDD:289631	7/22 (32%)
		C2H2 Zn finger	399..417	CDD:275368	6/17 (35%)
zfp-2	NP_496055.1	C2H2 Zn finger	173..194	CDD:275368	5/20 (25%)
		C2H2 Zn finger	202..222	CDD:275368	5/20 (25%)
		C2H2 Zn finger	231..251	CDD:275368	5/19 (26%)
		COG5048	<251..>358	CDD:227381	23/106 (22%)
		C2H2 Zn finger	257..278	CDD:275368	2/20 (10%)
		C2H2 Zn finger	302..322	CDD:275368	6/19 (32%)
		C2H2 Zn finger	330..350	CDD:275368	7/21 (33%)
		C2H2 Zn finger	358..374	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000